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Asian Journal of Biochemistry
  Year: 2007 | Volume: 2 | Issue: 6 | Page No.: 375-385
DOI: 10.3923/ajb.2007.375.385
Antitumor Activity of Urtica pilulifera on Ehrlich Ascites Carcinoma in Mice
M. Abdel-Kader , A.H. Mahmoud , H.M. Motawa , H.E. Wahba and A.Y. Ebrahim

Abstract:
The anti-tumor activity of 20% methanol extract of Urtica pilulifera was evaluated against the Ehrlich Ascites Carcinoma tumor model in mice. The activity was assessed using hematological studies, solid tumor mass and survival time. Intraperitoneal injection of Urtica pilulifera crude extract with different doses increased the survival time. Hematological parameters and packed cell volume, which were altered by tumor inoculation, were restored. Solid tumor mass was also significantly reduced. The bioactive compounds which produced these activities were isolated and identified as flavonoids and phenolic acids.
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How to cite this article:

M. Abdel-Kader , A.H. Mahmoud , H.M. Motawa , H.E. Wahba and A.Y. Ebrahim , 2007. Antitumor Activity of Urtica pilulifera on Ehrlich Ascites Carcinoma in Mice. Asian Journal of Biochemistry, 2: 375-385.

DOI: 10.3923/ajb.2007.375.385

URL: http://scialert.net/abstract/?doi=ajb.2007.375.385

 
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