The main objective of the study was to investigate about the anti hyperlipidemic
potential of the ethanolic extract from the fruits of Pedalium murex
at doses of 200 and 400 mg/kg/p.o. in high fat diet fed rats. Biochemical
parameters like serum total cholesterol (TC), High Density Lipoprotein
(HDL), Low Density Lipoprotein (LDL), very low density lipoprotein (VLDL)
and triglycerides (TG) levels were measured and compared with animals
concurrently treated with reference standards Gemfibrozil and Atorvastatin.
The ethanolic extract showed a significant decrease in triglycerides (p<0.01),
LDL (p<0.001), VLDL (p<0.01), cholesterol (p<0.001) and a significant
increase in HDL (p<0.05) levels at the tested doses.
Mukundh N. Balasubramanian, P. Muralidharan and G. Balamurugan, 2008. Anti Hyperlipidemic Activity of Pedalium murex (Linn.) Fruits
on High Fat Diet Fed Rats . International Journal of Pharmacology, 4: 310-313.