Antisickling activity of anthocyanins extract from a Congolese plant (Hymenocardia acida Tul.) was evaluated using Emmel test. Chromatographic separations using chloroform-benzene (2:1) provided three fractions A1, A2 and A3 with the most polar [A1 (TLC, Rf = 0.21)] exhibiting the highest activity. Thermal kinetic degradation of this fraction at 100 and 120°C produced a first order rate constants k = 2.64x10-4 and 4.08x10-4, respectively. Structural elucidation of isolated compounds is in progress.
P. T. Mpiana, V. Mudogo, Y. F. Kabangu, D.S. T. Tshibangu, K.N. Ngbolua, E. K. Atibu, K.P. Mangwala, M. B. Mbala, L. K. Makelele and M. T. Bokota, 2009. Antisickling Activity and Thermostability of Anthocyanins Extract from a Congolese Plant, Hymenocardia acida Tul. (Hymenocardiaceae). International Journal of Pharmacology, 5: 65-70.