Contrary to the sufficient availability of hundreds of papers
on how to report randomized clinical trials, less attention is paid on details
in design of randomized clinical trials specially on setting the objectives
and hypotheses. This study aimed to discuss some aspects of setting objectives
and hypotheses in randomized clinical trials. Interactively referring to several
examples in literature, this study have discussed different details of setting
objectives and hypotheses in randomized clinical trials and provided recommendations
on how to do it the best it can be.
H. Sadeghi-Bazargani and M.R. Sedghipour, 2012. Setting the Objectives and Hypotheses in Randomized Clinical Trials: Notices for Clinicians and Pharmacologists. International Journal of Pharmacology, 8: 475-482.