Abstract:
Thiram a fungicide used for treating corn and for storing
food grains were incorporated at 15, 30 and 60 ppm into the toxin free
diet of broiler chicken for four weeks from the day of hatch. The clinical
signs were reduced weight gain, lameness, abnormal bending of the tibial
bones, enlarged hock joints and sternal recumbency. Grossly tibial
dyschondroplasia was seen as a white opaque unmineralized cartilage plug
in the tibiotarsus. Histopathologically, tibiotarsus revealed thinning of
the growth plate, irregular arrangement of the proliferating layer,
abnormal thickening of the transitional layer and thickened hypertrophic
layer in the thiram fed groups. Changes were also seen in the liver, bile
duct, kidney, heart, crop, gizzard, intestine, lymphoid organs including
bursa, spleen and caecal tonsils and brain. There was no mortality at any
levels of thiram tested. Results of the present study thus revealed that
thiram at a level of even 15 ppm affected the health and performance of
broiler chicken.
S. Subapriya, S. Vairamuthu, B. Murali Manohar and C. Balachandran, 2007. Pathomorphological Changes in Thiram Toxicosis in Broiler Chicken. International Journal of Poultry Science, 6: 251-254.
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