The objective of this study was to elucidate the effects of C. olitorius as agent for relieving inflammation and fever. The aqueous extract of C. olitorius, in the concentration of 10, 50 and 100%, was used throughout the studies. The carrageenan-induced paw edema and brewer`s yeast-induced pyrexia assays were used as the anti-inflammatory and anti-pyretic assays, respectively. The extract, in the concentrations ranging from 50 to 100% and 10 to 100%, also exhibited significant (p<0.05) anti-inflammatory and anti-pyretic activities that lasted until the end of the experiments, respectively. In conclusion, the present studies provide scientific proof for the folklore medicinal used of C. olitorius as agent in the treatment of inflammation and fever.
Z.A. Zakaria, M.R. Sulaiman, A.K. Arifah, A.M. Mat Jais, M.N. Somchit, K. Kirisnaveni, D. Punnitharrani, M. Safarul, C.A. Fatimah and R. Johari, 2006. The Anti-inflammatory and Antipyretic Activities of Corchorus olitorius in Rats. Journal of Pharmacology and Toxicology, 1: 139-146.