This study was aimed to recognize factors effective
on weaning from mechanical ventilation and determine the reasons of unsuccessful
Spontaneous Breathing Trial (SBT) and reintubation. The study population
consisted of 202 critically ill pediatric patients who received mechanical.
When the patient was enrolled in the study, mechanical ventilation support
was stopped and the patient underwent a 2 h trial of Spontaneous Breathing
Trial (SBT), at the end of the trial if PaCO2 was in normal
range was extubated. Of the 202 patients who underwear SBT, 141 attempts
had successful trial. The remaining 61 patients had sign of poor tolerance
during the trial of spontaneous breathing and were reconnected to the
ventilator. One hundred and forty one patients (69.8%) successfully passed
the trial. 17 (12%) of above mentioned group required reintubation within
48-72 h. The overall success and failure rate was 61.3 and 38.7%, respectively.
Mortality rate in patients who did not tolerate SBT or were extubated,
or required reintubation were 13% (8 patients), 11.3% (14 patients) and
23.5% (4 patients), respectively. The most common reasons for reintubation
were neuromuscular disease (58.8%) congenital cardiac disease (23.5%)
and aspirative pneumonia (17.6%). The finding indicates that two third
of intubated patients, respond successfully to SBT and could be extubated
and the neuromuscular diseases is the main cause of reintubation.