The term of preterm birth is used to define the premature
neonates considering pregnancy age. In less than 34 week pregnancies, corticosteroids
are prescribed to promote embryos
lung maturity. The presents study aimed at evaluating effects of betamethasone
injection on feeling embryo motion by mother and index and biophysical profile
in preterm pregnancies. In a descriptive-analytical study, 40 pregnant women
with the pregnancy age of 30-34 weeks were evaluated. Embryo motion and index
and biophysical profile of the amniotic fluid were checked before prescription
of double dosage of muscular betamethasone (12 mg) at a 24 h time interval.
The injection was repeated for 24 and 48 h after the first injection. The resulted
outcomes were compared with those results related to before betamethasone injection.
In this study, there was statistically meaningful relationship between embryo
motions before injection of betamethasone and 12 h after its injection (p =
0.03). Also, there was a significant relationship between embryo motions 24
and 48 h after injection of betamethasone (p = 0.001). In other words, the embryo
motions decreased 12 h after injection of betamethasone. They were improved
48 h after betamethasone injection. But, index and biophysical profile results
of amniotic fluid were left unchanged. Application of betamethasone leads to
evident but transient decrease in embryo motions. Although motion element of
index and biophysical profile of amniotic fluid which is one of the tests used
in evaluating the embryo health is fixed and normal, it can be concluded that
injection of betamethasone may not affect embryo health.
Shamsi Abbasalizadeh, Zahra Neghadan Pharabar, Fatmeh Abbasalizadeh, Morteza Ghojazadeh and Mohamad Goldust, 2013. Efficacy of Betamethasone on the Fetal Motion and Biophysical Profile and Amniotic Fluid Index in Preterm Fetuses. Pakistan Journal of Biological Sciences, 16: 1569-1573.