Improvement in transplantation procedures, beginning with the advent of immunosuppressive therapies in the early 1980s, has lead to more and more patients benefiting from organ transplantation. At the same time, waiting lists of organ recipients are getting increasingly crowded. Tragically, the supply of donated organs has not kept pace with this demand. Even though each cadaveric organ donor can often supply multiple organs for transplantation, many patients still die before a suitable organ becomes available. This shortage results in a tragic number of potentially preventable deaths. Usually organs are retrieved from only about 15-20% of the eligible cadaveric donors available each year. Increased efforts to encourage organ donation could hence save many lives. However, there are a number of factors limiting the procurement of organs and accordingly, therapeutic cloning that perhaps can yield still better results needs to be considered as an alternative.