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Articles by K. Porteen
Total Records ( 2 ) for K. Porteen
  R. Manoj Kumar , R. Anbazhagan , C.C. Satheesh , V. Balamurugan , V. Mrudula and K. Porteen
  The vertebrate body is an ideal breeding ground for viruses and provides the conditions that promote their growth, survival and transmission. Vertebrates have developed immunity and at the same time the invading viruses have discovered elegant ways to circumvent the host`s immune mechanisms. One of the defense strategies that counteract the immune responses of the infected host exploits viral immunomodulators that directly interfere with the host`s cytokine system. Virus encoded immunomodulators (Virokines), enables viruses to create favorable habitat, which preserves them by protecting against damage from the inflammatory response, as well as by blocking apoptosis, until the virus replicates to high titers and finds another host. Virokines are clinically and therapeutically beneficial to the medical field and also having potential implications in viral epidemiology, treatment or prevention of viral and inflammatory diseases and for the development of safer vaccines. The endogenous secretion of the virus immunomodulators is thus emerging as an important mechanism of viral control, which is potentially inducible by effective vaccines. The in depth knowledge of the interactions between viruses and the virokines may lead to novel therapeutic and preventive strategies for the control of viral inflammatory diseases. There is no doubt that these virokines will serve as useful starting points for the development of new treatment tools in the new millennium.
  P. Selvan , S.K. Mendiratta , K. Porteen and K.N. Bhilegaonkar
  A study was carried out to determine the influence of different concentration and contact time combinations of lactic acid solutions on microbial, sensory and physico-chemical characteristics of buffalo offals viz., head meat, heart, liver and rumen. The following concentration and contact time combinations were used: 1% lactic acid for 20 sec, 1.5% lactic acid for 15 sec and 2% lactic acid for 10 sec. A total of 80 buffalo offal samples (20 numbers of each kind) were collected from a buffalo offal market and subjected to immersion treatments. Water washed offal pieces were used as controls. Sensory evaluations were conducted using a sensory panel comprising postgraduate students and scientists of Livestock Products Technology division, Indian Veterinary Research Institute (India). The data obtained were subjected to statistical analysis using the Analysis of Variance (ANOVA). Mean log10 reductions (CFU g 1) achieved, based on the different treatments and kinds of buffalo offal were between 0.22 and 1.05 for total viable counts; 0.22 and 1.19 for coliforms counts and 0.25 and 0.98 for staphylococcal counts. Immersion in 2% lactic acid solution for 10 sec gave the best overall reduction effect. Sensory evaluations recorded minimal effects of treatments on buffalo offals. These findings show that immersion in 2% lactic acid for 10 sec is suitable for decontamination of Buffalo Offals.
 
 
 
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