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Articles by M. Diouf
Total Records ( 3 ) for M. Diouf
  M. Diouf , E. Baudoin , L. Dieng , K. Assigbetse and A. Brauman
  This study characterized the genetic structure of the active soil bacterial populations involved in the decomposition of maize and soybean residues over 3 d. Significant compositional differences between the total bacterial community and its active component were observed that were residue specific, suggesting that residue management should be further evaluated as a driver of soil C cycle through selection of bacterial populations.
  F. Kajbaf , S. Fendri , A. Basille-Fantinato , M. Diouf , D. Rose , V. Jounieaux and J.-D. Lalau
 

Aims

Given that sleep disorders are known to be related to insulin resistance, and metformin has favourable effects on insulin resistance and on ventilatory drive, we sought to determine whether metformin therapy was related to sleep variables in a group of patients with Type 2 diabetes.

Methods

We performed a retrospective, observational study of our centre's database for patients referred for potential sleep disorders and then compared metformin-treated patients with those not treated with the drug. All study patients had undergone the same standard polysomnographic procedure. A multivariate analysis was performed to establish whether or not there was an independent relationship between metformin use and sleep variables (after adjusting for age, gender, BMI, neck circumference, cumulated risk factors and insulin use).

Results

We studied 387 patients (mean ± sd age: 58.4 ± 10.8 years), of whom 314 had been treated with metformin. Total sleep time and sleep efficiency were higher in metformin-treated patients than in patients not treated with metformin [total sleep time: 6 h 39 min vs. 6 h 3 min, respectively (P = 0.002); sleep efficiency: 77.9 ± 12.3 vs. 71.5 ± 17.2%, respectively (P = 0.003)]. These differences persisted after adjustment for covariates and were observed even although metformin users had a higher BMI than did non-users (median 37.5 vs. 34.8 kg/m2; P = 0.045).

Conclusion

We showed that metformin therapy is associated with a longer sleep duration and better sleep efficiency. Randomized clinical trials are needed to confirm metformin's favourable effect on sleep quality and quantity.

  S. Boureima , M. Eyletters , M. Diouf , T.A. Diop and P. Van Damme
  In order to study the effect of drought stress on germination indices in sesame (Sesamum indicum L.), a factorial experiment, using a completely randomized design with three replications was conducted. In this experiment, 22 confirmed sesame mutants induced through gamma ray treatment and their respective three parental sources were evaluated for five levels of drought stress (ψs= 0, -0.5, -1, -1.5 and -2 MPa) using aqueous solutions of PEG-6000. For each treatment, germination was checked every 48 h. Emerged seedling percentages as well as seedling root length were recorded after 7 days of experiment. Results evidence significant differences among genotypes and drought stress levels. Germination, emergence and root length were significantly reduced against control from a drought stress level ≤-1 MPa. Seeds did not germinate at all at an osmotic potential ≤-1.5 MPa whereas emergence was completely inhibited by -1 MPa. In present experimental conditions, a mild drought stress (-0.5 MPa) improved root growth in most genotypes studied as compared to controls. Emergence was the parameter the most affected by drought stress and germination the least affected. Genotypes hsc105, lc162, mc112, ef147 and hc107 were found to be more drought tolerant than their respective parents. Although sesame is reputed to be a drought tolerant crop, it is very susceptible to drought at germination stage and sufficient soil moisture is required for sesame seed emergence.
 
 
 
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