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Articles by V.O. Oyetayo
Total Records ( 6 ) for V.O. Oyetayo
  F.L. Oyetayo , V.O. Oyetayo and V. Ajewole
  This study aims at determination of the antimicrobial activity of the seeds extracts of Luffa cylindria on certain pathogenic microbes and screening for substances that may be responsible for these actions. Luffa cylindrica seeds and Leaves were extracted with ethanol, choloroform and methanol and screened for secondary metabolites. Extracts were found to contain alkaloids, saponnins and cardiac glycosides. The extracts also showed antimicrobial activities against Escherichia. coli, Staphylococcus aureus, Salmonella typhi and Bacillus subtilis. The zones of inhibition ranged between 6.00 to 10.00 mm. The inhibitory potentials of the extracts might be ascribed to their content of secondary metabolites. The ability of the extracts to inhibit the pathogens used as indicator organisms holds promise for potential application in the pharmaceutical industry.
  F.A. Igbasan , V.O. Oyetayo and O.O. Jawo
  The ability of faecal strains of Lactobacillus acidophilus source from faeces of albino rat (Lac A), human baby (Lac B) and pig (Lac P) to prevent diarrhea induced by Shigella dysenteriae in rats is reported. These faecal strains of Lactobacillus acidophilus were found to be effective in preventing Shigella dysenteriae induced diarrhea which was obvious in the Control (C) group alone. The probiotic lactobacilli also significantly improve Feed Conversion Ratio (FCR) and Total Weight Gain (TWG) of the rats. In terms of feed consumption, rats treated with Lactobacillus acidophilus consumed 11.15 to 17.58% feed less than C to achieve the same weight. The results of serum enzymes also reveal that there was no sign of toxicological effect when probiotic lactobacillus was administered to the rats. The serum Alkaline Phosphatase (ALP) of rats dosed with Lac A, Lac B and Lac P was lower and significantly different (p<0.05) when compared with C.
  V.O. Oyetayo and F.L. Oyetayo
  Preliminary in vivo study of the potential synergy of health promoting ability of Lactobacillus fermentum OVL and edible mushroom, Plerotus sajor-caju, was investigated in rats (Rattus norvegicus). From the results obtained, there was no obvious potential synergy between Lactobacillus fermentum OVL and Plerotus sajor-caju in promoting the growth performance of rats dosed with Lactobacillus fermentum OVL and placed on diet compounded from the mushroom, Plerotus sajor-caju (MDL). The daily weight gain (DWG), feed conversion ratio (FCR), and protein efficiency ratio (PER) were better in control (PD) placed on diet compounded with casein than in diet compounded from mushroom (MD and MDL). However, there were obvious potential synergy between Lactobacillus fermentum OVL and Plerotus sajor-caju in stimulating the immune response of the host. The serum globulin in treatment MD and MDL (38.33mg/dl and 46.87mg/dl respectively) were higher and significantly different (P<0.05) from control (PD). There was also a potential synergy in the ability of Lactobacillus fermentum OVL and Plerotus sajor-caju in bringing about an increase in the count of beneficial lactobacilli in the faeces of rats in treatments MD and MDL having faecal lactobacilli count of 6.81 cfu/g and 7.32 cfu/g respectively when compared with control (PD) with 6.66 cfu/g that was lower and significantly different (P<0.05).
  F.I. Aboderin and V.O. Oyetayo
  The effect of oral administration of different doses of probiotic, Lactobacillus plantarum, isolated from fermenting corn slurry on the haematological parameters of wistar albino rats was investigated. Sixteen (16) rats divided into four groups (A, B, C and D) of four rats per group were used. Group A was placed on the basal diet alone, while group B, C and D were placed on the diet and also dosed with 0.3ml, 0.6ml, and 1.0ml of 107 cfu/ml of reconstituted lyophilized culture of Lactobacillus plantarum respectively. In rats treated with different doses of Lactobacillus plantarum there was a significant increase in the packed cell volume (PCV), haemoglobin and red blood cell (RBC) when compared with the control. Moreover, the differential leucocyte counts reveal an increase in the lymphocyte count of the rats dosed with Lactobacillus plantarum when compared to the control except in rats dosed with 1.0ml of 107 cfu/ml of the probiotic, which was not significantly different (P<0.05) from the control. There was also a significant increase (P<0.05) in the weight gain by rats fed Lactobacillus plantarum when compared to the control. The data obtained showed that Lactobacillus plantarum isolated from fermenting corn slurry is safe and it has immunostimulatory effect and can also improve the performance of rats in terms of weight gain.
  V.O. Oyetayo , F.C. Akharaiyi and M. Oghumah
  Water samples sourced from wells in Akure metropolis was analyzed to determine the E. coli counts. Out of the 12 water samples randomly obtained, 58.33% were observed to be laden with E. coli. The E. coli counts ranged between 10-59 cfu mL-1 which was well above WHO recommended value of no E. coli in 100 mL. The study also revealed that E. coli isolates from the wells have different antibiotic sensitivity pattern. The isolates obtained from Araromi and FUTA junction were less sensitive to the antibiotics while isolates from Ilesa garage and rescue hostel were more sensitive to the different antibiotics. The isolates were found to be more sensitive to norfloxacin (100%, gentamycin (100%, ciprofloxacin (100%), chloramphenicol (85.71%) and teramycin (71.43%).
  V.O. Oyetayo and R.M. Ilori
  Microbial quality of the air in the main operating theater, male and female surgical wards of State Specialist Hospital Akure was assessed. The female surgical ward was found to have the highest Total Viable Count (TVC) of 42.25 cfu/plate while the least TVC was recorded in the main operating theater (3.25 cfu/plate). The bacteria isolated from the different sections sampled include Escherichia coli, Staph. aureus, Proteus mirabilis, Klebsiella pneumoniae and Bacillus subtilis. Antibiotic sensitivity test reveal different sensitivity pattern of bacteria even within the same species. The antibiotics that were found to be most effective are Clindamycin (90.90%), Cloxacillin (81.81%), Norfloxacin (81.81%), Daravid (81.81%), Ciprofloxacin (72.73%) and Chloraphenicol (72.73%). Hospital management are advised to monitor the quality of the hospital environment periodically to know the bacterial pathogens that are prevalent and the effective antibiotics against such pathogens.
 
 
 
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