Asian Journal of Epidemiology1992-14622077-205XAsian Network for Scientific Information10.3923/aje.2017.63.69BibenVitriana DefiIrma Ruslina NugrahaGaga Irawan SetiabudiawanBudi 22017102Background and Objective: Vitamin D status is correlated with musculoskeletal function. Yet, normal cut-off values for vitamin D status vary across studies and remain a subject of debate. This study design to find out a cut-off value of vitamin D in community-dwelling elderly individuals in Indonesia, examine vitamin D status based of the new cut-off value and vitamin D associations with various body characteristics that associate with musculoskeletal function. Materials and Methods: A cross-sectional study consisted of 263 community-dwelling elderly individuals in Bandung and Sumedang, West Java province, Indonesia were enrolled between July and December, 2015. Vitamin D status was calculated using adjusted vitamin D cut-off value that determined based on parathyroid hormone suppression through receiver operating characteristic analysis. Correlation analysis then used to found out vitamin D association with muscle mass, muscle strength and body fat. Results: Most subjects (94.3%) were vitamin D insufficient-deficient based on the adjusted cut-off value (≤36.0 ng mL1). Vitamin D status was correlated with muscle mass (r = 0.239, p = 0.000), muscle strength (r = 0.324, p = 0.000) and also negatively correlated with percentage of body fat (r = !0.261, p = 0.000) significantly. Conclusion: Hypovitaminosis D is a common condition in community-dwellings elderly individuals in Indonesia. Its association with muscle mass, muscle strength and body fat, highlight the need for comprehensive recommendations, such as education for adequate nutrition intake, sun exposure, physical activity and consideration of vitamin supplementation in rational way should be considered and designed.]]>Palacios, C. and L. Gonzalez,2014144138145Choi, S.W., S.S. Kweon, J.S. Choi, J.A. Rhee and Y.H. Lee et al.,20152015Marantes, I., S.J. Achenbach, E.J. Atkinson, S. Khosla, L.J. Melton and S. Amin,20112628602871Zhou, J., P. Huang, P. Liu, Q. Hao, S. Chen, B. Dong and J. Wang,2016947076Halfon, M., O. Phan and D. Teta,20152015Pojednic, R.M. and L. Ceglia,2014427681Low, S., M.C. Chin, S. Ma, D. Heng and M. Deurenberg-Yap,2009386669Verdoia, M., A. Schaffer, L. Barbieri, G. di Giovine, P. Marino, H. Suryapranata and G. de Luca,201525464470Al-Horani, H., W. Abu Dayyih, E. Mallah, M. Hamad, M. Mima, R. Awad and T. Arafat,20162016Holick, M.F.,2009197378Chen, L.K., L.K. Liu, J. Woo, P. Assantachai and T.W. Auyeung et al.,20141595101Nimitphong, H. and M.F. Holick,201353437Rodrigo, M., M. Hettiarachchi, C. Liyanage and S. Lekamwasam,2013519972003Cashman, K.D., M. Kiely, M. Kinsella, R.A. Durazo-Arvizu and L. Tian et al.,20139712351242Setiati, S.,2008407883Holmes, E.W., J. Garbincius and K.M. McKenna,2013140550560Vogeser, M.,2010121565573Hosseinpanah, F., S.H. Pour, M. Heibatollahi, N. Moghbel, S. Asefzade and F. Azizi,20102010Lips, P.,2010121297300Van Dam, R.M., M.B. Snijder, J.M. Dekker, C.D. Stehouwer, L.M. Bouter, R.J. Heine and P. Lips,200785755761Pourshahidi, L.K.,201574115124Cipriani, C., J. Pepe, S. Piemonte, L. Colangelo, M. Cilli and S. Minisola,20142014Liu, G., L. Lu, Q. Sun, X. Ye and L. Sun et al.,201411415441551Ceglia, L.,200829407414Garcia, L.A., K.K. King, M.G. Ferrini, K.C. Norris and J.N. Artaza,20112 vitamin D3 stimulates myogenic differentiation by inhibiting cell proliferation and modulating the expression of promyogenic growth factors and myostatin in C2C12 skeletal muscle cells.]]>15229762986Ceglia, L., S. Niramitmahapanya, M. da Silva Morais, D.A. Rivas and S.S. Harris et al.,201398E1927E1935Salles, J., A. Chanet, C. Giraudet, V. Patrac and P. Pierre et al.,20132‐vitamin D3 enhances the stimulating effect of leucine and insulin on protein synthesis rate through Akt/PKB and mTOR mediated pathways in murine C2C12 skeletal myotubes.]]>5721372146Buitrago, C.G., N.S. Arango and R.L. Boland,20122D3‐dependent modulation of Akt in proliferating and differentiating C2C12 skeletal muscle cells.]]>11311701181Girgis, C.M.,201417546550Bruyere, O., E. Cavalier, J.C. Souberbielle, H.A. Bischoff-Ferrari and C. Beaudart,20142014Vimaleswaran, K.S., D.J. Berry, C. Lu, E. Tikkanen and S. Pilz et al.,20132013