International Journal of Pharmacology1811-77751812-5700Asian Network for Scientific Information10.3923/ijp.2011.829.835Tamarix aphylla Leaf Extract]]>Soliman YusufogluHasan Ibrahim AlqasoumiSaleh 8201178Tamarix aphylla, a traditionally used plant in the Middle Eastern countries, was screened for its potential antioxidant, anti-inflammatory and wound healing effect. Antioxidant activity of T. aphylla ethanolic leaf extract was measured by 1, 1, diphenyl, 2 picryl, hydrazyl and hydrogen peroxide free radicals scavenging method. Herbal gel formulations containing 15 and 25% T. aphylla extract in gel base, namely Carbapol-934, were prepared. Further herbal gel formulations were evaluated for its anti-inflammatory activity by carrageen an induced paw edema model and wound healing activity by excision wound model in Wister rats. Percentage, reduction in paw edema and wound contraction was measured in these models. The extract showed maximum scavenging activity i.e., 80.81±0.29 and 67.76±0.09 at 400 μg mL-1 by 1, 1, diphenyl, 2 picryl, hydrazyl and hydrogen peroxide free radicals scavenging method, respectively. In carrageen an induced paw edema model and excision wound model, the formulation showed optimum percentage inhibition of 53.07 and 89.6% with 25% gel formulation which was comparable to the standard Diclomax® and Betadine®, respectively. The Present study concludes that T. aphylla leaves extract, possesses antioxidant, anti-inflammatory and wound healing activities.]]>Abbas, B., A.A. Al-Qarawi and A. Al-Hawas,200250367379Abdel-Rahman, F. and M.A. Saleh,200638258303Asif, M. and A. Kumar,2009Dalbergia sissoo (Roxb.) bark.]]>73950Azaizeh, H., B. Saad, K. Khalil and O. Said,20063229235Bhat, R.S., J. Shankrappa and H.G. Shivakumar,200721117Brooks, P.M. and R.O. Day,199132417161725Cosio, M.S., S. Buratti, S. Mannino and S. Benedetti,200697725731Gabbaiani, G., B.J. Harschel, G.B. Ryan, P.R. Statkov and G. Majno,1972135719734Heneidy, S.Z. and L.M. Bidak,2004710101023Kamal, M., S.M. Wazir, M. Hassan, M. Subhan, S.U. Khan, M. Muhammad and S. Taj,2009158793Kellogy, E.W. and I. Fridovich,197525088128817Leite, S.N., G. Palhano, S. Almeida and M.W. Biavatti,2002Vernonia scorpioides extract in guinea pig.]]>73496500Lira, A.A.M., E.A. Sester, A.L.M. Carvalho, R.R. Strattmann, M.M. Albuquerque, A.G. Wanderley and D.P. Santana,20089163168Nawwar, M.A.M. and S.A.M. Hussein,1994Tamarix aphylla.]]>3610351037Maier, C.M. and P.H. Chan,20028323334Marwah, R.G., M.O. Fatope, R.A. Mahrooqi, G.B. Varma, H.A. Abai and S.A.S. Al-Burtamani,2007101465470Marwat, S.K., M.A. Khan, M.A. Khan, Fazal-ur-Rehman, M. Ahmad, M. Zafar and S. Sultana,2009Salvadora persica, Tamarix aphylla and Zizyphus mauritiana-three woody plant species mentioned in Holy Quran and Ahadith and their ethnobotanical uses in North Western Part (D.I. Khan) of Pakistan.]]>8542547Merfort, I., J. Buddrusa, M.A.M. Nawwara and J. Lamberta,1992Tamarix aphylla.]]>3140314032Mughal, T., S. Shahid and S. Qureshi,2011Withania coagulans and Tamarix aphylla.]]>3289294Nawwar, M.A.M., S.A.M. Hussein, N.A. Ayoub, K. Hofmann and M. Linscheid et al.,2009Tamarix aphylla flowers.]]>64342347Ogunlana, O.E., O. Ogunlana and O.E. Farombi,2008Newbouldia laevis on selected free radicals.]]>2249254Ratty, A.K., J. Sunamoto and N.P. Das, 198837989995Di Rosa, M., P.J. Giroud and D.A. Willoughby,19711011529Ruch, R.J., K.A. Crist and J.E. Klaunig,1989100451464Shafaghat, A.,201096166Shetty, S., S. Udupa and L. Udupa,2008Ocimum sanctum Linn. in rats.]]>595101Subhan, N., M.A. Alam, F. Ahmed, M.A. Awal, L. Nahar and S.D. Sarker,2008In vitro antioxidant property of the extract of Excoecaria agallocha (Euphorbiaceae).]]>16149154Vadlapudi, V.R., V. Bobbarala and K.C. Naidu,2009210621064Vinegar, R., J.F. Truax, J.L. Selph, P.R. Johnston, A.L. Venable and K.K. McKenzie,198746118126