Kidney Research Journal1819-33742154-3836Academic Journals Inc.10.3923/krj.2016.1.84-induced Renalotoxicity in Albino Rats]]>IbukunE.O. OladipoG.O. 1201661Objective: This study was aimed at evaluating the renaloprotective effect of alcoholic red wine against CCl4-induced toxicity. Methodology:In vitro antioxidant activity of the alcoholic red wine was typified by total antioxidant activity, ABTS, DPPH and hydroxyl radicals, reducing power and metal chelating activities. In vivo evaluation of the ameliorative effect of alcoholic red wine against CCl4-renalotoxicity was experimented on kidney function by the profiling of biochemical indices, such as alkaline phosphatase (ALP) activity, creatinine clearance, Total Protein (TP) and the antioxidant status evaluated by activities of superoxide dismustase (SOD), glutathione peroxidase (GSH-Px), catalase (CAT) and glutathione-S-transferase (GST). Results: The results revealed that extracts of red wine had total antioxidant activity value of 96.57±6.441 mg g1 AAE. Conclusion: The study revealed that the alcoholic red wine has ameliorative effect, which did not nullify the effect of the toxicological stress in all of the results.]]>Burns, J., P.T. Gardner, J. O'Neil, S. Crawford and I. Morecroft et al.,200048220230Mattivi, F., R. Guzzon, U. Vrhovsek, M. Stefanini and R. Velasco,20065476927702St. Leger, A.S., A.L. Cochrane and F. Moore,197931310171020Renaud, S. and M. de Lorgeril,199233915231526Di Castelnuovo, A., L. Iacoviello and G. De Gaetano,200334817191722Slater, T.F. and B.C. Sawyer,1971in vitro. General features of the systems used.]]>123805814DeShon, N.D.,19791979pp: 704-714pp: 704-714Sakata, T., N. Watanabe, N. Hobara and H. Nagashima,198738959961Venkov, C.D., P.R. Myers, M.A. Tanner, M. Su and D.E. Vaughan,199981638642Leikert, J.F., T.R. Rathel, P. Wohlfart, V. Cheynier, A.M. Vollmar and V.M. Dirsch,200210616141617Oyaizu, M.,198644307315Leong, L.P. and G. Shui,2002766975Re, R., N. Pellegrini, A. Proteggente, A. Pannala, M. Yang and C. Rice-Evans,19992612311237Haro-Vicente, J.F., C. Martinez-Gracia and G. Ros,2006in vitro measurement of available iron from different fortificants in citric fruit juices.]]>98639648Halliwell, B., J.M.C. Gutteridge and O.I. Aruoma,1987165215219Adewole, S.O., A.A. Salako, O.W. Doherty and T. Naicker,200710153164Weichselbaum, T.E.,1946104049Englehardt, A.,1970164243Kakkar, P., B. Das and P.N. Viswanathan,198421130132Tappel, A.L.,197852506513Johansson, L.H. and L.A. Borg,1988174331336Ellman, G.L.,1959827077Hissin, P.J. and R. Hilf,197674214226Habig, W.H., M.J. Pabst and W.B. Jakoby,197424971307139Noguchi, T., K.L. Fong, E.K. Lai, S.S. Alexander and M.M. King et al.,198231615624Al-Fartosi, K.G., A. Majid, M.A. Auda and M.H. Hussein,20124.]]>3385389Aleynik, S.I., M.A. Leo, X. Ma, M.K. Aleynik and C.S. Lieber,199727554561Al-Sowayan, N.S. and H.M. Mousa,201411238242Guiraud, A., M. De Lorgeril, S. Zeghichi, F. Laporte and P. Salen et al.,200810012371244Gu, X., L. Creasy, A. Kester and M. Zeece,19994732233227Walker, G., D. Kunz, W. Pignat, I. Wiesenberg, H. Van den Bosch and J. Pfeilschifter,19962 in rat renal mesangial cells.]]>306265270Recknagel, R.O., E.A. Glende, Jr., J.A. Dolak and R.L. Waller,198943139154Halliwell, B. and J.M. Gutteridge,20003rd Edn.,pp: 148-149pp: 148-149Yamamoto, Y. and S. Yamashita,19999241246Bandyopadhyay, U., D. Das and R.K. Banerjee,199977658666Anandan, R., R.D. Rekha and T. Devaki,1999Picrorhiza kurroa on mitochondrial glutathione antioxidant system in D-galactosamine-induced hepatitis in rats.]]>7615431545