The Distribution of Glutathione and Glutathione S-transferase Activity in the Organs of Dhub (The Agamid Lizard; Uromastyx aegyptius)


	Journal of Biological Sciences
	Year: 2007 \| Volume: 7 \| Issue: 3 \| Page No.: 558-561 DOI: 10.3923/jbs.2007.558.561

The Distribution of Glutathione and Glutathione S-transferase Activity in the Organs of Dhub (The Agamid Lizard; Uromastyx aegyptius)

Mohammed Abdel Aziz Sarhan and Ahmed Al-Qahtani

Abstract: Distribution of total and reduced glutathione in addition to the glutathione S-transferase activities in Dhub (Uromastyx aegyptius) tissues was investigated. Studies GSH and GST are of interest because of its involvement in the detoxification and bioactivation of xenobiotics. In this study liver showed the highest level of total glutathione (6.019±1.38 µmol g^-1 wet tissue), whereas, the heart has the lowest level (1.753±0.255 µmol g^-1 wet tissue). Reduced glutathione (GSH) was three times higher in the liver than in the heart. The distribution of glutathione S-transferase activity was examined in the liver, kidney, lung and heart. The bulk of glutathione S-transferase activity was found in the liver (3.75 µmol min^-1 mg^-1 protein) and the lowest in the heart (0.27 µmol min^-1 mg^-1 protein).

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How to cite this article:

Mohammed Abdel Aziz Sarhan and Ahmed Al-Qahtani , 2007. The Distribution of Glutathione and Glutathione S-transferase Activity in the Organs of Dhub (The Agamid Lizard; Uromastyx aegyptius). Journal of Biological Sciences, 7: 558-561.

DOI: 10.3923/jbs.2007.558.561

URL: https://scialert.net/abstract/?doi=jbs.2007.558.561

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