Gabriela V. G- Verduzco
Departamento de Produccion Animal, Aves, FMVZ, UNAM,CD. Universitaria, Mexico City, Mexico D.F. 04510
Guillermo Tellez
Department of Poultry Science, University of Arkansas, Fayetteville, AR 72701, USA
Michael H. Kogut
Southern Plains Agricultural Research Center, USDA-ARS, 2881,F and B Road, College Station, TX 77845, USA
Armando Isibasi
Unidad de Investigacion Medica en Inmunoquimica del Hospital de Especialidades del Centro Medico Nacional del IMSS, Mexico City, Mexico, D.F. 03020
Vianney Ortiz- Navarrete
Departamento de Biomedicina Molecular del Centro de Investigacion y de Estudios Avanzados del IPN (CINVESTAV), Mexico City, Mexico, D.F. 07360
ABSTRACT
Investigations in our laboratories have indicated that an increased resistance to Salmonella enteritidis SE organ infectivity in chickens was conferred by the immunoprophylactic administration of SE-immune lymphokines (SE-ILK). Resistance has been associated with an enhanced heterophilic accumulation within 4 h of ILK injection. Further studies demonstrated that CxCLi2 is produced locally by the host in response to both the SE infection and the SE-ILK suggesting that IL-8 is a major chemotactic factor produced by the host, which aids in mediating the SE-ILK induced recruitment of heterophils to the site of SE invasion. In the present study, two bio-assays confirmed the presence of IFN and IL-2 functions in SE-ILK that may also participate in the establishment of the reported protection against Salmonella infections. The IL-2 and IFN effects detected in this work suggest that birds immune response develops similarly to that of mammals, with some features corresponding to the species.
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How to cite this article
Gabriela V. G- Verduzco, Guillermo Tellez, Michael H. Kogut, Armando Isibasi and Vianney Ortiz- Navarrete, 2009. Presence of Interferon-Gamma and IL-2 in Supernatants of Salmonella enteritidis-Immune Lymphokines. International Journal of Poultry Science, 8: 820-823.
DOI: 10.3923/ijps.2009.820.823
URL: https://scialert.net/abstract/?doi=ijps.2009.820.823
DOI: 10.3923/ijps.2009.820.823
URL: https://scialert.net/abstract/?doi=ijps.2009.820.823
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