Asian Journal of Animal and Veterinary Advances1683-99191996-3289Academic Journals Inc.10.3923/ajava.2016.242.247AlyMahmoud A. SalehNahed S. AllamTamer S. KeshtaHany G. 42016114Objective: This study aimed to evaluate the clinical and laboratory metabolic alterations in left displaced abomasum cattle with particular emphasis on the oxidative effects. Methodology: Cows with left displaced abomasum were confirmed on the basis of clinical symptoms. Blood samples were collected from 12 diseased cows during 4-6 weeks after parturition and were assayed for the selected biochemical parameters. Another 10 healthy cows were selected from similar environmental conditions and served as control. Results: The results showed that serum values of glucose, urea, creatinine, aspartate aminotransferase and amylase were significantly increased in the left displaced abomasum cows whereas, a significant decrease was found in serum concentrations of total protein, albumin, cholesterol, calcium, phosphorus, sodium, potassium and chloride. Metabolic alkalosis was evidenced by the significant elevation in blood bicarbonate concentrations plus pH. Oxidant-antioxidant study revealed a significant increase in the levels of hydrogen peroxide, nitric oxide and malondialdehyde in the diseased group while, serum enzymatic activities of catalase and glutathione reductase demonstrated a significant decrease. Conclusion: It was concluded that oxidative stress appeared to contribute in the pathogenesis of abomasal displacement in cattle and thus using of anti-oxidant therapies is recommended both to prevent and treat the disease.]]>Sevinc, M., M. Ok and A. Basoglu,2002153477480Aslan, V., M. Ok, M. Boydak, I. Sen, F.M. Birdane and F. Alkan,20032003Dezfouli, M.M., Z. Eftekhari, S. Sadeghian, A. Bahounar and M. Jeloudari,201322175179Van Winden, S.C.L., R. Jorritsma, K.E. Muller and J.P.T.M. Noordhuizen,20038614651471Radostits, O.M., C.C. Gay, K.W. Hinchcliff and P.D. Constable,20072007pp: 353-374pp: 353-374Shaver, R.D.,19978024492453Cameron, R.E.B., P.B. Dyk, T.H. Herdt, J.B. Kaneene and R. Miller et al.,199881132139Detilleux, J.C., Y.T. Grohn, S.W. Eicker and R.L. Quaas,199780121126Constable, P.D., G.Y. Miller, G.F. Hoffsis, B.L. Hull and D.M. Rings,19925311841192Zadnik, T.,200353297309El-Attar, H.M., M. Yassein, Y.M. Abd El-Raof and M.M. Ghanem,200716102109Staric, J., H.S. Biricik, G. Aksoy and T. Zadnik,201079469473Holtenius, K., K. Sternbauer and P. Holtenius,20007819301935Rohn, M., B.A. Tenhagen and W. Hofmann,200451300305Geishauser, T. and C. Seeh,199643445450Stengarde, L., M. Traven, U. Emanuelson, K. Holtenius, J. Hultgren and R. Niskanen,20082008Itoh, N., M. Koiwa, A. Hatsugaya, H. Yokota, H. Taniyama, H. Okada and K. Kudo,199845293298LeBlanc, S.J., K.E. Leslie and T.F. Duffield,200588159170Roussel, A.J., M.S. Whitney and D.J. Cole,199792553568Sahinduran, S. and M.K. Albay,2006157352356Jorgensen, R.J., N.R. Nyengaard, S. Hara, J.M. Enemark and P.H. Andersen,199839331338Amanzadeh, J. and R.F. Reilly Jr.,20062136148Devrim, A.K., M. Sozmen, K. Yigitarslan, M. Sudagidan, O. Kankavi and H.I. Atabay,20127368372Pryor, W.A.,198648657667Maden, M., S.A. Ozturk, A. Bulbul, G.E. Avci and E. Yazar,20122614701475Doll, K., M. Sickinger and T. Seeger,20091819096Demir, S., M. Yilmaz, M. Koseoglu, N. Akalin, D. Aslan and A. Aydin,2003143943Mamak, N., A.K. Devrim, H. Aksit, I. Aytekin and R. Yildiz,201316731733Hasanpour, A., N. Saranjam and B.A. Tabrizi,20117478481