Current Research in Chemistry1996-50522152-3385xAsian Network for Scientific Information10.3923/crc.2019.1.7ZelelewDemis MekassaBerhanu 12019111Background and Objectives: The consumption of food products from animal origin and environmental exposure remain the main sources of organochlorine pesticides residues (OCPs) in human diets. This study assessed levels of OCPs in poultry feed obtained from three feed mills in north shewa Zone, Ethiopia. Materials and Methods: The proximate analysis was carried out using method described by AOAC and analysis of organochlorine pesticides with GC-ECD. Results: The proximate analysis mean levels are as follows: Moisture {broiler feed (6.33±0.8%), layer mash ( 7.00±1.8%)}, ash {broilers (8.33±2.6%), layers (9.17±4.9%)}, fibre {broilers (0.33±0.2%), layers (0.20±0.2%)}, dry matter {broilers (93.7±0.8%), layers (93.0±1.7%)}. The mean OCPs values ranged from 0.34-14.8 ng kg1 in broilers and 0.20-5.22 ng kg1 in layers mash. In broilers feed, aldrin, endosulfan I and endrin, exceeded the Maximum Residue Limits (MRL) for animal feed for OCPs, while in layers mash, aldrin and endrin aldehyde exceeded the MRL limits. Conclusion: These results indicated the presence of organochlorine pesticides in poultry feeds which could bioaccumulate and eventually lead to the contamination of table eggs and table meats as a result of these endocrine disruptors. The study observed that from the detected analytes seven of them above the international MRL values and suggested that stringent monitoring of use of pesticides in poultry feed and food of animal origin is required.]]>Ozcan, C.,2015137075Abulude, F.O., Y.S. Akinjagunla and A. Omoniyi,20061911Benbrook, C.M.,200256822823Mahmoudi, R., M. Zangishah and H. Hasannejad,20167138150Lehotay, S.J., K. Mastovska and S.J. Yun,200588630638Salar-Amoli, J. and T. Ali-Esfahani,20156155159International Agency for Research on Cancer,19871987Bilrha, H., R. Roy, B. Moreau, M. Belles-Isles, E. Dewailly and P. Ayotte,2003In vitro activation of cord blood mononuclear cells and cytokine production in a remote coastal population exposed to organochlorines and methyl mercury.]]>11119521957Lavoie, E.T. and K.A. Grasman,2007in ovo exposure to PCBs 126 and 77 on mortality, deformities and post-hatch immune function in chickens.]]>70547558Suleiman, N., E.B. Ibitoye, A.A. Jimoh and Z.A. Sani,2015131721Aycicek, M., O. Kaplan and M. Yaman,2008Helianthus annus L.).]]>2026632672Oluyemi, J.A. and F.A. Roberts,20002nd Edn.,Bernhoft, A., J.U. Skaare, O. Wiig, A.E. Derocher and H.J.S. Larsen,2000Ursus maritimus) at Svalbard.]]>59561574Bukar, H. and M.D. Saeed,201571624CSA.,20072007Cochran, W.G.,19773rd Edn.,AOAC.,200518th Edn.,pp: 69-77pp: 69-77Gayathri, D., C.K. Gyana and N. Padmaja,2007218790Aulakh, R.S., J.P.S. Gill, J.S. Bedi, J.K. Sharma, B.S. Joia and H.W. Ockerman,200686741744Olomu, J.M.,19791979pp: 241268Gillespie, A.M. and S.M. Walters,19891216871703Van der Hoff, G.R., A.C. van Beuzekom, A.T. Udo, R.A. Baumann and P. van Zoonen,1996754487496Ahmad, R., N.M. Salem and H. Estaitieh,201078667671ATSDR.,20022002CETESB.,20082008Botaro, D., J.P.M. Torres, O. Malm, M.F. Rebelo, B. Henkelmann and K.W. Schramm,20114921252130Tao, S., W.X. Liu, X.Q. Li, D.X. Zhou and X. Li et al.,2009157497502