Current Research in Cardiovascular Pharmacology2152-193x2152-1956Academic Journals Inc.10.3923/crcpaj.2017.1.16MishraSanjay Kumar Mani TiwariAmit Ali MahdiAbbas 1201761The metabolic disorder affects about 30% of the US population with escalating prevalence. In this study, the relationships between the metabolic disorder and the occurrence and rigorousness of cardiovascular disease in common and coronary artery disease in particular were explored. The impression of metabolic disorder on outcomes of coronary revascularization therapies and coronary collateral development was specifically compiled. Besides, the association between the metabolic disorder and its individual component pathologies and oxidative stress were also examined. Researchers discuss the apparent lack of encouraging influence of antioxidants on cardiovascular consequences in enormous clinical trials with stress on some of the restrictions of these trials. Lastly, researchers highlight verification for booming application of antioxidant assets of pharmacological agents, including metformin, statins, angiotensin II type I receptor blockers and angiotensin II converting enzyme inhibitors for preclusion and management of the cardiovascular impediments of the metabolic disorder.]]>Grundy, S.M.,200828629636Wilson, P.W.F., W.B. Kannel, H. Silbershatz, R.B. D'Agostino,199915911041109Suzuki, T., K. Hirata, M.S.V. Elkind, Z. Jin and T. Rundek et al.,2008156405410Ford, E.S., W.H. Giles and A.H. Mokdad,20042724442449Sookoian, S. and C.J. Pirola,200713747Arnlov, J., E. Ingelsson, J. Sundstrom and L. Lind,2010121230236Noda, H., H. Iso, I. Saito, M. Konishi, M. Inoue and S. Tsugane,200932289298Lassegue, B. and K.K. Griendling,201030653661Cavalca, V., F. Veglia, I. Squellerio, G. Marenzi and F. Minardi et al.,200939267272Deanfield, J., A. Donald, C. Ferri, C. Giannattasio and J. Halcox et al.,200523717Munzel, T., C. Sinning, F. Post, A. Warnholtz and E. Schulz,200840180196Suessenbacher, A., M. Potocnik, J. Dorler, G. Fluckinger and M. Wanitschek et al.,2011107945948Flammer, A.J., T. Anderson, D.S. Celermajer, M.A. Creager and J. Deanfield et al.,2012126753767Sharma, V., S. Kalim, M.K. Srivastava, S. Nanda and S. Mishra,200944258Azumi, H., N. Inoue, Y. Ohashi, M. Terashima and T. Mori et al.,20022218381844Folli, F., D. Corradi, P. Fanti, A. Davalli and A. Paez et al.,20117313324Fortuno, A., G.S. Jose, M.U. Moreno, O. Beloqui, J. Diez and G. Zalba,200655209215Hansel, B., P. Giral, E. Nobecourt, S. Chantepie, E. Bruckert, M.J. Chapman and A. Kontush,20048949634971Roberts, C.K., R.J. Barnard, R.K. Sindhu, M. Jurczak, A. Ehdaie and N.D. Vaziri,200655928934Ford, E.S., A.H. Mokdad, W.H. Giles and D.W. Brown,20035223462352Perticone, F., R. Ceravolo, M. Candigliota, G. Ventura, S. Iacopino, F. Sinopoli and P.L. Mattioli,200150159165Montero, D., G. Walther, A. Perez-Martin, E. Roche and A. Vinet,201213441455Rector, R.S., S.O. Warner, Y. Liu, P.S. Hinton and G.Y. Sun et al.,2007293E500E506Roberts, C.K., D. Won, S. Pruthi, S. Kurtovic, R.K. Sindhu, N.D. Vaziri and R.J. Barnard,200610016571665Kelishadi, R., M. Hashemi, N. Mohammadifard, S. Asgary and N. Khavarian,200854147153Furukawa, S., T. Fujita, M. Shimabukuro, M. Iwaki and Y. Yamada et al.,200411417521761Houstis, N., E.D. Rosen and E.S. Lander,2006440944948De Mattia, G., M.C. Bravi, O. Laurenti, A. Moretti and R. Cipriani et al.,200879337342De Oliveira, J., M.A. Hort, E.L.G. Moreira, V. Glaser and R.M. Ribeiro-do-Valle et al.,201119799106De Mattos, A.M., L.V. Marino, P.P. Ovidio, A.A. Jordao, C.C. Almeida and P.G. Chiarello,2012166874Zelzer, S., N. Fuchs, G. Almer, R.B. Raggam and F. Pruller et al.,201141213451349Andreadou, I., D. Farmakis, E. Prokovas, F. Sigala and A. Zoga et al.,201294501509Ansari, J.A., U. Bhandari, K.K. Pillai and S.E. Haque,201250216222Ward, N.C., J.M. Hodgson, I.B. Puddey, T.A. Mori, L.J. Beilin and K.D. Croft,200436226232Redon, J., M.R. Oliva, C. Tormos, V. Giner, J. Chaves, A. Iradi and G.T. Saez,20034110961101Wang, D., S. Strandgaard, J. Iversen and C.S. Wilcox,2009296R195R200Abdilla, N., M.C. Tormo, M.J. Fabia, F.J. Chaves, G. Saez and J. Redon,2007216875Chen, H.J. and W.H. Pan,20071510961100Monami, M., N. Marchionni, G. Masotti and E. Mannucci,20079350353Sanchez, R., P. Fischer, L. Cuniberti, L.D. Masnatta and A.J. Ramirez,20072524342440Cottone, S., G. Mule, E. Nardi, A. Vadala and M.C. Lorito et al.,200725423428Somers, M.J., K. Mavromatis, Z.S. Galis and D.G. Harrison,200010117221728Landmesser, U., H. Cai, S. Dikalov, L. McCann and J. Hwang et al.,2002phox in vascular oxidative stress and hypertension caused by angiotensin II.]]>40511515Heitzer, T., U. Wenzel, U. Hink, D. Krollner and M. Skatchkov et al.,199955252260Rajagopalan, S., S. Kurts, T. Munzel, M. Tarpey, B.A. Freeman, K.K. Griendling and D.G. Harrison,19969719161923Freedman, D.S., W.H. Dietz, S.R. Srinivasan and G.S. Berenson,199910311751182Berenson, G.S., S.R. Srinivasan, W. Bao, W.P. Newman, R.E. Tracy and W.A. Wattigney,199833816501656Galili, O., D. Versari, K.J. Sattler, M.L. Olson and D. Mannheim et al.,2007292H904H9011Kelly, A.S., J. Steinberger, D.R. Kaiser, T.P. Olson, A.J. Bank and D.R. Dengel,20061248252Ghio, A.J., M.S. Carraway and M.C. Madden,201215121Chuang, K.J., C.C. Chan, T.C. Su, C.T. Lee and C.S. Tang,2007176370376Mills, N.L., K. Donaldson, P.W. Hadoke, N.A. Boon and W. MacNee et al.,200963644Zanobetti, A., M. Franklin, P. Koutrakis and J. Schwartz,20092009Tonstad, S. and M. Svendsen,20059616811685Nanda, S., S. Mishra, V.P. Varshney and R.B. Singh,201038193Chen, C.C., T.C. Li, P.C. Chang, C.S. Liu and W.Y. Lin et al.,200857544548Nakatani, D., Y. Sakata, H. Sato, H. Mizuno and M. Shimizu et al.,200799885889Zhang, J., S. Jiang and R.R. Watson,200110910071009Chen, H., M.S. Goldberg and P.J. Viileneuve,200823243298Henrotin, J.B., M. Zeller, L. Lorgis, Y. Cottin, M. Giroud and Y. Bejot,20109619901996Mustafic, H., P. Jabre, C. Caussin, M.H. Murad and S. Escolano et al.,2012307713721Brook, R.D., S. Rajagopalan, C.A. Pope III, J.R Brook and A. Bhatnagar et al.,201012123312378Pereira Filho, M.A., L.A.A. Pereira, F.F. Arbex, M. Arbex and G.M. Conceicao et al.,200841526532Bateson, T.F. and J. Schwartz,200415143149Park, S.K., A.H. Auchincloss, M.S. O'Neill, R. Prineas and J.C. Correa et al.,201011814061411Cotrim, H.P., F. Carvalho, A.C. Siqueira, M. Lordelo, R. Rocha and L.A. De Freitas,200529416151620Sirit, Y., C. Acero, M. Bellorin and R. Portillo,200810239249Mohan, V., M. Deepa, S. Farooq, D. Prabhakaran and K.S. Reddy,200821813Lang, I.A., T.S. Galloway, A. Scarlett, W.E. Henley, M. Depledge, R.B. Wallace and D. Melzer,200830013031313Sakurai, K., M. Kawazuma, T. Adachi, T. Harigaya, Y. Saito, N. Hashimoto and C. Mori,2004141209214Prozialeck, W.C., J.R. Edwards, D.W. Nebert, J.M. Woods, A. Barchowsky and W.D. Atchison,2008102207218Wang, S.L., J.M. Chiou, C.J. Chen, C.H. Tseng and W.L. Chou et al.,2003111155159Mahfuzar, R., M. Tondel, S.A. Ahmad and O. Axelson,1998148198203Afridi, H.I., T.G. Kazi, N. Kazi, M.K. Jamali and M.B. Arain et al.,200880280288Navas-Acien, A., E.K. Silbergeld, R. Pastor-Barriuso and E. Guallar,2008300814822Paul, D.S., A.W. Harmon, V. Devesa, D.J. Thomas and M. Styblo,2007115734742Sun, Q., P. Yue, J.A. Deiuliis, C.N. Lumeng and T. Kampfrath et al.,2009119538546Esposito, K., R. Marfella, M. Ciotola, C. Di Palo and F. Giugliano et al.,200429214401446Cottone, S., G. Mule, E. Nardi, A. Vadala and M. Guarneri et al.,200619313318Abramson, J.L., W.C. Hooper, D.P. Jones, S. Ashfaq and S.D. Rhodes et al.,2005178115121Fito, M., M. Cladellas, R. de la Torre, J. Marti and M. Alcantara et al.,2005181149158John, J.H., S. Ziebland, P. Yudkin, L.S. Roe and H.A.W. Neil,200235919691974Basu, A., K. Sanchez, M.J. Leyva, M. Wu, N.M. Betts, C.E. Aston and T.J. Lyons,2010293140Stancliffe, R.A., T. Thorpe and M.B. Zemel,201194422430Antonini-Canterin, F., S. La Carrubba, G. Gullace, C. Zito and V. di Bello et al.,201061443448Kawamoto, R., H. Tomita, N. Ohtsuka, A. Inoue and A. Kamitani,2007147885Iglseder, B., P. Cip, L. Malaimare, G. Ladurner and B. Paulweber,20053612121217Kip, K.E., O.C. Marroquin, D.E. Kelley, B.D. Johnson and S.F. Kelsey et al.,2004109706713Roger, V.L., A.S. Go, D.M. Lloyd-Jones, R.J. Adams and J.D. Berry et al.,2011123e18e209Kim, J.Y., H.S. Mun, B.K. Lee, S.B. Yoon and E.Y. Choi et al.,201051676682Schernthaner, G.,199631S3S13Lakka, H.M., D.E. Laaksonen, T.A. Lakka, L.K. Niskanen, E. Kumpusalo, J. Tuomilehto and J.T. Salonen,200228827092716Kotur-Stevuljevic, J., L. Memon, A. Stefanovic, S. Spasic and V. Spasojevic-Kalimanovska et al.,200740181187Meisinger, C., J. Baumert, N. Khuseyinova, H. Loewel and W. Koenig,2005112651657Kajimoto, K., T. Kasai, K. Miyauchi, H. Hirose and N. Yanagisawa et al.,20087214811486Brackbill, M.L., C.S. Sytsma and K. Sykes,200918468473Hoffmann, R., E. Stellbrink, J. Schroder, A. Grawe and G. Vogel et al.,2007Sirolimus-eluting stents.]]>10013471352Yaginuma, K., T. Kasai, K. Miyauchi, K. Kajimoto, A. Amano and H. Daida,201152372376Marso, S.P., J.W. Murphy, J.A. House, D.M. Safley and W.S. Harris,200523136Almalla, M., J. Schroder, V. Deserno, F. Vogt and R. Koos et al.,201022317321Hu, R., C. Ma, S.P. Nie, Q. Lu and J.P. Kang et al.,200611918711876Onishi, T., K. Shimada, S. Sunayama, H. Ohmura and T. Sumide et al.,200953381387Sung, S.H., T.C. Wu, C.H. Huang, S.J. Lin and J.W. Chen,201197648654Foody, J.M., F.D. Ferdinand, G.L. Pearce, B.W. Lytle, D.M. Cosgrove and D.L. Sprecher,2000102III-90III-94Yun, J., P. Rocic, Y.F. Pung, S. Belmadani, A.C.R. Carrao, V. Ohanyan and W.M. Chilian,20091119611974Yilmaz, M.B., V. Caldir, Y. Guray, U. Guray and H. Altay et al.,200697636639Sasmaz, H. and M.B. Yilmaz,200960164168Mouquet, F., F. Cuilleret, S. Susen, K. Sautiere and P. Marboeuf et al.,200930840849Reed, R., C. Kolz, B. Potter and P. Rocic,2008286167Hattan, N., W.M. Chilian, F. Park and P. Rocic,2007102217223Weihrauch, D., N.L. Lohr, B. Mraovic, L.M. Ludwig and W.M. Chilian et al.,200410923432348Lassaletta, A.D., L.M. Chu, M.P. Robich, N.Y. Elmadhun and J. Feng et al.,20122012Mohri, M., H. Tomoike, M. Noma, T. Inoue, K. Hisano and M. Nakamura,198964287296Yamanishi, K., M. Fujita, A. Ohno and S. Sasayama,199024271277Rocic, P., C. Kolz, R. Reed, B. Potter and W.M. Chilian,2007292H2729H2736Pung, Y.F., P. Rocic, M.P. Murphy, R.A. Smith and J. Hafemeister et al.,201232325334Reed, R., B. Potter, E. Smith, R. Jadhav, P. Villalta, H. Jo and P. Rocic,2009296H1811H1821Miller, S.J., B.J. Coppinger, X. Zhou and J.L. Unthank,200947108114Lonn, E., J. Bosch, S. Yusuf, P. Sheridan and J. Pogue et al.,200529313381347Knekt, P., J. Ritz, M.A. Pereira, E.J. O'Reilly and K. Augustsson et al.,20048015081520Halliwell, B.,200035511791180Meagher, E.A., O.P. Barry, J.A. Lawson, J. Rokach and G.A. FitzGerald,200128511781182Czernichow, S., A.C. Vergnaud, P. Galan, J. Arnaud and A. Favier et al.,200992329335Demircan, N., A. Gurel, F. Armutcu, M. Unalacak, E. Aktunc and H. Atmaca,200814CR97CR101Beydoun, M.A., M.R. Shroff, X. Chen, H.A. Beydoun, Y. Wang and A.B. Zonderman,2011141903913Cangemi, R., F. Angelico, L. Loffredo, M. Del Ben, P. Pignatelli, A. Martini and F. Violi,200743853859Basu, A., N.M. Betts, J. Ortiz, B. Simmons, M. Wu and T.J. Lyons,201131190196Upston, J.M., A.C. Terentis, K. Morris, J.F. Keaney and R. Stocker,2002363753760Lee, S.H., T. Oe and I.A. Blair,200129220832086Boaz, M., S. Smetana, T. Weinstein, Z. Matas and U. Gafter et al.,200035612131218Heinecke, J.W.,20023210901101Hou, X., J. Song, X.N. Li, L. Zhang, X. Wang, L. Chen and Y.H. Shen,2010396199205Bellin, C., D.H. de Wiza, N.F. Wiernsperger and P. Rosen,200638732739Alhaider, A.A., H.M. Korashy, M.M. Sayed-Ahmed, M. Mobark, H. Kfoury and M.A. Mansour,2011192233242Meaney, E., A. Vela, V. Samaniego, A. Meaney and J. Asbun et al.,200835895903Yusuf, S., P. Sleight, J. Pogue, J. Bosch, R. Davies and G. Dagenais,2000342145153Yusuf, S., K.K. Teo, J. Pogue and L. Dyal et al.,200835815471559Harrison, D.G., H. Cai, U. Landmesser and K.K. Griendling,200345161Griendling, K.K., C.A. Minieri, J.D. Ollerenshaw and R.W. Alexander,19944711411148Cingolani, O.H., N.G. Perez, I.L. Ennis, M.C. Alvarez and S.M. Mosca et al.,2011In vivo key role of reactive oxygen species and NHE-1 activation in determining excessive cardiac hypertrophy.]]>462733743Khan, B.V., S. Sola, W.B. Lauten, R. Natarajan and W.C. Hooper et al.,20042717121715Yoshida, J., K. Yamamoto, T. Mano, Y. Sakata and N. Nishikawa et al.,200443686691Henriksen, E.J.,2007293R974R980Henriksen, E.J., S. Jacob, T.R. Kinnick, M.K. Teachey and M. Krekler,200138884890Oltman, C.L., T.L. Kleinschmidt, E.P. Davidson, L.J. Coppey, D.D. Lund and M.A. Yorek,2008484753Al-Thanoon, Z.A. and I.H. Mahmood,2012272730Csibi, A., D. Communi, N. Muller and S.P. Bottari,20102010Wei, Y., J.R. Sowers, R. Nistala, H. Gong and G.M.E. Uptergrove et al.,20062813513735146Gogebakan, A., Z.S. Talas, I. Ozdemir and E. Sahna,201234424428Talas, Z.S., I. Ozdemir, O. Ciftci, O. Cakir, M.F. Gulhan and O.M. Pasaoglu,201436492496