Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2007.2237.2240BakhtiarianAzam EjtemaimehrShahram StroblSylvia Pournaghash-TehraniSaid PartoazarAlireza GhamamiGuiti YasaNarges 1220071013In this research anti-inflammatory effect of Tripleurospermum disciforme extract was studied in rats. The effect of the extract against acute inflammation was studied by hind paw edema test. Intraperitoneal injection of different doses (15, 30, 45, 60, 90 and 120 mg kg-1) of Tripleurospermum disciforme which was followed by hind paw carageenan injection 1 h later were investigated. The resultant edema was quantified by measuring changes of diameter of hind foot. After 2, 3, 4 and 6 h we measured the anti-inflammatory effect of Tripleurospermum disciforme extract. Tripleurospermum disciforme extract with doses of 45, 60, 90 and 120 mg kg-1 and indomethacin 5 mg kg-1 showed significant effect. It is concluded that Tripleurospermum disciforme extract has anti-inflammatory effect against acute inflammation.]]>Appelt, G.D.,1985Matricaria chamomilla.]]>135155Avallone, R., P. Zanoli, G. Puia, M. Kleinschnitz, P. Schreier and M. Baraldi,2000Matricaria chamomilla.]]>5913871394Budzinski, J.W., B.C. Foster, S. Vandenhoek and J.T. Arnason,2000in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures.]]>7273282Clement, Y., F.W. Arlene, D. Aranda, R. Chase and N. Watson et al.,2005533Dale, M.,1994pp: 280-282pp: 280-282Fidler, P., C.L. Loprinzi, J.R. O'Fallon, J.M. Leitch and J.K. Lee et al.,199677522525Goodman and Gilman's,200110th Edn.,pp: 661pp: 661Maday, E.,199924303308Renuka, C.,1992pp: 62pp: 62Yarosh, D.B., J.W. Galvin, S.L. Nay, A.V. Pena, M.T. Canning and D.A. Brown,2006Evodia rutaecarpa extract from traditional Chinese medicine.]]>421321