Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2007.3688.3692Aedes aegypti (Diptera: Culicidae) in 2006 to Pyrethroid Insecticides in Indonesia and its Association with Oxidase and Esterase Levels]]>AhmadIntan AstariSita TanMarselina 1220071020Three strains of Aedes aegypti collected in 2006 from three major cities in Indonesia, i.e., Bandung, Palembang and Surabaya, were tested to determine their resistance status to pyrethroid (permethrin and deltamethrin) and also the resistance mechanisms regarding three detoxifying enzymes, i.e., oxidase, esterase A and esterase B. The resistance level was expressed as Resistance Ratio (RR) compared to the susceptible VCRU strain. Results of this study showed that Ae. aegypti in Indonesia has developed tolerance to permethrin and deltamethrin, except in the Bandung strain, which was resistant to permethrin and deltametherin with RR90 79.3 and 23.7, respectively. The study also suggested that detoxifying enzymes (oxidase, esterase A and esterase B) apparently were involved in the development of resistance in Bandung strain as indicated by the high level of activity of those enzymes in Bandung strain compared to other more susceptible strains. Although there is a possibility that other mechanisms, such as a target-site resistance mechanism, in Bandung strain were also involved.]]>Arief, R.,2000Aedes aegypti from four cities in West Java to the Propoxur, Malathion, Permethrin and Esbiothrin.]]>2000Astari, S. and I. Ahmad,2005Aedes aegypti (Linn.) (Diptera: Culicidae) against insecticides permethrin, cypermethrin and D-allethri.]]>337379Brengues, C., N.J. Hawkes, F. Chandre, L. McCarroll and S. Duchon et al.,2003Aedes aegypti is correlated with novel mutations in the voltage-gated sodium channel gene.]]>178794Chareonviriyaphap, T., P. Rongnoparut and P. Juntarumporn,2002Anopheles minimus species A, a malaria vector in Thailand.]]>27222229Chareonviriyaphap, T., P. Rongnoparut, P. Chantarumporn and M.J. Bangs,2003Anopheles minimus in Thailand.]]>28108116Ganesh, K.N., J. Urmila, P. Guillet and L. Manga,2003Anopheles stephensi (Liston) and A. culicifacies (Giles) from Mysore, India.]]>1173038Kerkut, G.A. and L.I. Gilbert,1985Vol. 12,Leksono, A.S.,1997Aedes aegypti (L.) (Diptera: Culicidae) terhadap malathion dengan seleksi 8 generasi.]]>1997Macoris, M.L.G., M.T.M. Andrighetti, L. Takaku, C.M. Glasser, V.V. Garbeloto and J.E. Bracco,2003Aedes aegypti from Sao Paolo Brazil to organophosphate insecticides.]]>98703708Ponlawat, A., J.G. Scott and L.C. Harrington,2005Aedes aegypti and Aedes albopictus across Thailand.]]>42821825Valles, S.M., P.G. Koehler and R.J. Brenner,19979012541258Vulule, J.M., R.F. Beach, F.K. Atieli, J.C. McAllister and W.G. Brogdon et al.,1999Anopheles gambiae from Kenyan villages using permethrin-impregnated nets.]]>13239244WHO,19861986Yaicharoen, R., R. Kiatfuengfoo, T. Chareonviriyaphap and P. Rongnoparut,2005Aedes aegypti in Thailand.]]>30144150