Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2008.275.279EbrahimzadehMohammad Ali ShokrzadehMohammad RamezaniAhmad 22008112The main goal of this study was to compare the utilization
of antibiotics in different wards of a university hospital. Consumption
of antibacterial drugs rose dramatically during years 2000-2005 in Iran.
Data collected during first half of year 2000 and 2005 in Emam University
Hospital in city of Sari in Iran, showed use of antibiotics jumped from
95.4 DBDs (Defined Daily Doses per patient`s bed-days) to 124 DBDs. Distribution
of different class of anti-microbial showed highest increase in use of
vancomycin with 28.4 folds and clindamycin with 4.8 fold. Use of cotrimoxazole,
aminoglycosides and tetracyclines remained fairly unchanged during this
period. However, during the same period, consumption of penicillin G,
aminopenicillins and cloxacillin dropped 10.3, 3.8 and 3 fold, respectively.
Among university hospital departments, oncology ward followed by ICU and
general surgery consumed the most antibacterial agents in year 2000. In
year 2005, ICU ward followed by gynecology, oncology and orthopedic were
among the University Hospital Departments with highest consumption of
antibiotics. The most highly used antibiotics in year 2000 were cefazolin
followed by ampicillin, ceftizoxime and gentamicin. In year 2005, cefazolin,
ceftriaoxone, gentamicin and ciprofloxacin were the most prescribed antibiotics.
Injectable antibiotics accounted for 51.8 and 79.4% of total DBDs in first
half of years 2000 and 2005, respectively. The bulk of prescription (90%
of total DBDs) was made up of 13 out of 32 total antibiotic types in 2000
and 11 out of 29 total antibiotics types in 2005. Comparing with similar
hospitals in other countries, data presented show a dramatic increase
in antibiotics prescribed by physician in Emam University Hospital.]]>Bergan, T.,200118279282Cars, O., S. Mlstad and A. Melander,200135718511853Dancer, S.J., M. Coyne, C. Robertson, A. Thomson, A. Guleri and S. Alcock,200662200206De-With, K., E. Meyer, M. Steib-Bauert, F. Schwab, F.D. Daschner and W.V. Kern,200664231237Ebrahimzadeh, M.A., M.R. Mahdavi and M. Asadee,20055449452Ebrahimzadeh, M.A., M.R. Mahdavi and M. Vahedi,2005E. coli isolated from urine: A 2-year study on isolates from patients with UTIs in Iran.]]>5445448Ebrahimzadeh, M.A., M.R. Mahdavi and E. Salimi,20066555557Hsueh, P.R., W.H. Chen and K.T. Luh,200526463472Kolar, M., K. Urbanek and T. Latal,200117357363Mahdavi, M.R., M.A. Ebrahimzadeh, S.S. Saeedi and K.H. Shabanian,20066803806Malacarne, P., C. Rossi and G. Bertolini,200454221224Mantel-Teeuwisse, A.K., O.H. Klungel, W.M.M. Verschuren, A. Porsius and A.D. Boer,20015411811186Melander, E., K. Ekdahl, G. Jnsson and S. Mlstad,20001911721177Cristino, J.M., 19991299202Natsch, S., Y.A. Hekster, R.D. Jong, E.R. Heerdink, R.M.C. Herings and J.W.M. Van-der-Meer,1998172024Abdinnour-Helm, S.F., B.S. Chaparro and S.M. Farmer,1999107989996Rogues, A.M., B. Placet-Thomazeau, P. Parneix, I. Vincent and M.C. Ploy et al.,200458187192Sintchenko, V., J.R. Iredell, G.L. Gilbert, E. Coiera,200512398402Vaccheri, A., L. Bjerrum, D. Resi, U. Bergman and N. Montanaro,200250989997Walther, S.M., M. Erlandsson and L.G. Burman,20024610751081WHO,2000Wise, R., T. Hart and O. Cars,1998317609610With, K.D., J. Bergner, R. Bühner, F . Dörje and C . Gonnermann et al.,200424213218