Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2011.698.702Helicobacter pylori in Outpatient Setting]]>FakhrjouA. SomiM.H. FattahiE. KoohbananiS.S. ShadravanS. 1220111412Helicobacter pylori (HP) is a common cause of gastric infection with serious consequences which is detected by different methods. This study aimed at comparing the diagnostic value of Rapid Urease Test (RUT), Touch Cytology (TC) and histopathologic assessment in outpatients setting. In this cross-sectional study, 51 candidates for upper gastrointestinal endoscopy were recruited in Tabriz Imam Khomeini Teaching Centre in a 24 month period of time. Three biopsy specimens were obtained from gastric antrum during endoscopic intervention. The RUT, TC and histopathologic assessment were performed on each biopsy specimen in each patient. Definite infection by HP was considered when at least 2 out of 3 tests indicated presence of infection. Fifty one patients, 29 females and 22 males with a mean age of 40.10±12.54 (range: 18-72) years enrolled in this study. Infection by HP was definite in 41 cases (80.4%). The infection rates by RUT, TC and histopathologic examination were 82.4, 82.4 and 76.5%, respectively. The sensitivity, specificity and accuracy of RUT, TC and histopathologic assessment were 92.7, 60 and 66.75%; 100, 90 and 98% and 95.1, 100 and 96.1%, respectively. There were significant agreements between outcomes of the three methods in diagnosis of infection by HP. In conclusion, TC was the most sensitive and histopathologic assessment was the most specific method in diagnosis of infection by HP in outpatient setting. The diagnostic value of RUT was rather low in this regard.]]>Cibas, E.S. and B.S. Ducatman,20093rd Edn.,Pages: 537Pages: 537Day, D.W. and B.C. Morson,20034th Edn.,Pages: 692Pages: 692Debongnie, J.C., J. Mairesse, M. Donnay and X. Dekoninck,199411811151118Genta, R.M., G.O. Robason and D.Y. Graham,1994Helicobacter pylori and gastric morphology: A new stain.]]>25221226Hashemi, M.R., M. Rahnavardi, B. Bikdeli, M. Dehghani Zahedani and F. Iranmanesh,2008Helicobacter pylori: Comparison of four staining methods.]]>19179184Khedmat, H., M. Amini, A.M. Jafari, F.N. Afshar and M. Izadi,2007Helicobacter pylori Infection with seasonal behavior of duodenal ulcer.]]>713041309Kolts, B.E., B. Joseph, S.R. Achem, T. Bianchi and C. Monteiro,1993Helicobacter pylori detection: A quality and cost analysis.]]>88650655Cotran, R.S., V. Kumar, T. Collins and S.L. Robbins,19996th Edn.,Pages: 1425Pages: 1425Mendoza, M.L., P. Martin-Rabadan, I. Carrion, J.D. Morillas, G. Lopez-Alonso and M. Diaz-Rubio,1993Helicobacter pylori infection. Rapid diagnosis with brush cytology.]]>37181185Mills, S.E.,20073rd Edn.,Pages: 1272Pages: 1272Nahaei, M.R., Y. Sharifi, M.T. Akhi, M. Asgharzadeh, M. Nahaei and E. Fatahi,2008Helicobacter pylori cagA and vacA genotypes and their relationships to peptic ulcer disease and non-ulcer dyspepsia.]]>3386394Moghaddam, M.N., M.A. Khajeh-Karamoddin and M. Ramezani,2009In vitro anti-bacterial activity of sweet basil fractions against Helicobacter pylori.]]>9276279Moghaddam, M.N. and M.N. Moghaddam,2008Helicobacter pylori clinical isolates in a hospital in Iran and protein pattern of two strains showing differences in susceptibility.]]>8466469Pinto, M.M., F.V. Meriano, S. Afridi and H.L. Taubin,1991Campylobacter pylori in papanicolaou-stained imprints of gastric biopsy specimens.]]>35204206Rasmi, Y., M. Sadreddini, M. Jamali, T. Peirouvi and F. Khosravifar,2009Helicobacter pylori in peptic ulcer disease: difference between gastric and duodenal ulcer disease.]]>9146150Rosai, J. and L.V. Ackerman,20049th Edn.,Pages: 3135Pages: 3135Sadeghifard, N., M.M. Aslani and A. Ghasemi,2006Helicobacter pylori.]]>611461149Mahmood, S. and A. Hamid,2010Helicobacter pylori infection.]]>13509512Saksena, S., S. Dasarathy, K. Verma, V. Ahuja and M.P. Sharma,2000Helicobacter pylori.]]>196163Sheikhian, A., S. Ataherian, M. Delfan, F. Ebrahimzadeh and Y. Pournia,2011Helicobacter pylori infection among health center referrals in Khorramabad (West of Iran).]]>418Suhaila, N., S. Hussin and M.M. Rahman,2010Helicobacter pylori.]]>1310571061Tokunaga, Y., H. Shirahase, E. Yamamoto, R. Inao and S. Hamaguchi et al.,2000Helicobacter pylori detection in relation to an immunohistochemical stain.]]>15617621Trevisani, L., S. Sartori, M. Ruina, M. Caselli, V. Abbasciano, E. Grandi and E. Forini,1997Helicobacter pylori infection.]]>4222992303Yamamoto, T.,2001Helicobacter pylori infection.]]>75856862Zamani, A. and K. Daneshjou,2006Helicobacter pyloriin 6-12 Year-old healthy primary school students of the 19 educational sectors of Tehran-Iran.]]>62733