Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2014.1074.1078Toxoplasma gondii Infection among HIV-infected
Pregnant Women in Bobo-Dioulasso, Burkina Faso]]>BambaS. SourabieY. GuiguemdeT.R. KarouD.S. SimporeJ. BambaraM. VillenaI. 92014179The deficit of cellular immunity, as found in HIV infected individuals, may lead to the reactivation of latent Toxoplasma gondii cysts, with as consequence, the occurrence of toxoplasmosis and an eventual vertical transmission of the disease during pregnancy. The present study was designed for determining the occurrence of latent Toxoplasma gondii among HIV-infected pregnant women during the first trimester in Bobo-Dioulasso. Thus, 348 pregnant women aged from 17 to 47 years (average age of 6.64±4.75yaers) were enrolled. The specific anti-Toxoplasma gondii IgG and IgM antibodies were quantified from whole blood specimens using the high-sensitivity direct agglutination and the enzyme linked fluorescent assays, respectively, the IgG avidity test being used for the dating of the primary infection. The results revealed that the seroprevalence of Toxoplasma gondii latent infection was 34.7%. It was significantly higher in HIV-infected women compared with uninfected ones (68,7%; CI 95%: 43,6%-88,9%) versus (33,1%; CI 95%: 28, 2%-38,3%). In addition, all the occurrences of the high IgG avidity were closely linked with the presence of IgM. These results underlined the need for the clinical follow-up of the maternal HIV diseases including the toxoplasmosis during the pregnancy since; the newborns are still exposed to vertical transmission of Toxoplasma infection in endemic areas like Burkina Faso.]]>Bachmeyer, C., G. Mouchnino, P. Thulliez and L. Blum,200652e55e57Desmonts, G. and J.S. Remington,1980Toxoplasma infection: Method for increasing sensitivity and specificity.]]>11562568Dunn, D., M. Wallon, F. Peyron, E. Petersen, C. Peckham and R. Gilbert,199935318291833Dubey, J.P. and J.L. Jones,2008Toxoplasma gondii infection in humans and animals in the United States.]]>3812571278Fernandes, M.A., G.I. Batista, C. Carlos Jda, I.M. Gomes and K.M. Azevedo et al.,2012Toxoplasma gondii antibody profile in HIV-1-infected and uninfected pregnant women and the impact on congenital toxoplasmosis diagnosis in Rio de Janeiro, Brazil.]]>16170174Kieffer, F. and M. Wallon,201311210991101Kodjikian, L., I. Hoigne, O. Adam, P. Jacquier, C. Aebi-Ochsner, C. Aebi and J.G. Garweg,200423272274Koblavi-Deme, S., C. Maurice, D. Yavo, T.S. Sibailly and K. N'guessan et al.,20013918081812Liesenfeld, O., J.G. Montoya, S. Kinney, C. Press and J.S. Remington,2001Toxoplasma gondii infection in pregnant women: Experience in a US reference laboratory.]]>18312481253Lima, L.H. and M.C. Viana,200925668676Marty, P., A. Bongain, S. Loiseau, B. Benoit, A. Chevallier, J.Y. Gillet and Y. Le Fichoux,20023115581558Maschke, M., O. Kastrup, S. Esser, B. Ross, U. Hengge and A.J. Hufnagel,200069376380Miller, M.J., W.J. Aronson and J.S. Remington,196971139145Mitchell, C.D., S.S. Erlich, M.T. Mastrucci, S.C. Hutto, W.P. Parks and G.B. Scott,19909512518Passos, L.N., O.F.A. Filho and H.F. Andrade Jr.,200042141145Pelloux, H., E. Brun, G. Vernet, S. Marcillat and M. Jolivet et al.,1998Toxoplasma gondii immunoglobulin G avidity: Adaptation to the Vidas system (bioMerieux).]]>326973Purner, M.B., R.L. Berens, S. Tomavo, L. Lecordier, M.F. Cesbron-Delauw, B.L. Kotzin and T.J. Curiel,1998Toxoplasma gondii-seronegative persons by proteins derived from T. gondii.]]>177746753Safadi, M.A., E.N. Berezin, C.K. Farhat and E.S. Carvalho,20037325331Simpore, J., A. Savadogo, D. Ilboudo, M.C. Nadambega and M. Esposito et al.,2006Toxoplasma gondii, HCV, and HBV seroprevalence and co-infection among HIV-positive and -negative pregnant women in Burkina Faso.]]>78730733Sitoe, S.P.B.L., B. Rafael, L.R. Meireles, H.F. de Andrade Jr. and R. Thompson,2010Toxoplasma gondii occurrence in pregnant women from Mozambique.]]>52291295Weiss, L.M. and J.P. Dubey,200939895901