Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2015.46.49Chromolaena odorata]]>AsomughaR.N. EzejioforA.N. OkaforP.N. IjehI.I. 12015181Chromolaena odorata, a commonly used traditional remedy
for different ailments, believed to be quite safe in terms of toxicity was evaluated
for acute toxicity and cytotoxic potentials. Acute toxicity was done on albino
Wistar rats using the Lorke method while brine shrimps were used to test for
cytotoxicity. The results showed that the estimated LD50 for the
aqueous and ethanolic extracts was 2154 and >5000 mg kg-1 body
weight, respectively. Cytotoxicity to brine shrimps showed LC50 values
of 324 and 392 ppm for aqueous and ethanolic extracts, respectively. These results
indicate the relative non toxic nature of Chromolaena odorata extracts.]]>Farnsworth, N.R., O. Akerele, A.S. Bingel, D.D. Soejarto and Z. Guo,198563965981Fett Neto, A.G. and F. DiCosmo,1992Taxus cuspidata.]]>58464466Kupchan, S.M., R.J. Hemingway, A. Karim and D. Werner,1969Vernonia amygdalina del.]]>3439083911Koba, K., G. Catherine, C. Raynaud, J. Chaumont, K. Sanda and N. Laurence,2009Chenopodium ambrosioides L. Essential Oil from Togo.]]>44435440Lagnika, L., E. Anago and A. Sanni,20115773777Lorke, D.,198354275287Mabberley, D.J.,19972nd Edn.,pp: 858pp: 858McLaughlin, J.L., C.J. Chang and D.L. Smith,19931993pp: 112-137pp: 112-137Meyer, B.N., N.R. Ferrigni, J.E. Putnam, L.B. Jacobsen, D.E. Nichols and J.L. McLaughlin,1982453134Moshi, M.J., E. Innocent, J.J. Magadula, D.F. Otieno, A. Weisheit, P.K. Mbabazi and R.S.O. Nondo,2010126367Pala, N.A., A.K. Negi and N.P. Todaria,201085761Phan, T.T., L. Wang, P. See, R.J. Grayer, S.Y. Chan and S.T. Lee,2001Chromolaena odorata protect cultured skin cells from oxidative damage: Implication for cutaneous wound healing.]]>2413731379Solecki, R.S.,1975190880881Leeuwen, C.J. and T.G. van Vermeire,2007Pages: 240Pages: 240Prabhu, V., I. Sujina, H. Hemlal and S. Ravi,2011in-vitro cytotoxic activity of fresh leaves of Chromolaena odorata.]]>446094611Vital, P.G. and L.W. Rivera,2009Chromolaena odorata (L. f.) King and Robinson and Uncaria perrottetii (A. Rich) Merr. extracts.]]>3511518Harborne, J.B., 19842nd Edn.,