Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2021.235.240Zamioculcas zamiifolia (Lodd.) Engl. Extracts]]>RattanasukSurachai PhiwthongTannatorn 22021242Background and Objective: The increase of antibiotic-resistant bacteria is a problem for global health that needs to find new antibiotic drugs. The plant is the potential source of antibiotic substances that important to solve the antibiotic-resistant bacteria. This study was aimed to evaluate the antibacterial activity of Zamioculcas zamiifolia stem extracts against nine human pathogenic bacteria. Materials and Methods:Z. zamiifolia stems were extracted with five extraction solvents. The screening of antibacterial activity of stem extract was measured using agar disc diffusion assay. The Minimal Inhibition Concentration (MIC) and Minimal Bactericidal Concentration (MBC) values of extracts were determined using the broth microdilution assay and colorimetric assay. Results: The results indicated that the lowest MIC value of 0.09 mg mL1 against Staphylococcus aureus TISTR 1466 was obtained from hexane extraction. The lowest MBCs value of 1.56 mg mL1 against Bacillus cereus TISTR 2373, Listeria spp. and Escherichia coli TISTR 527 were obtained from ethanol and methanol extractions. Conclusion: The ethanolic and methanolic stem extracts of Z. zamiifolia demonstrated the highest anti-human pathogenic bacterial activity. This is the first report to demonstrate the high potential of antibacterial substance from Z. zamiifolia stem extracts, which can be developed further as a natural drug for treating bacterial infectious diseases.]]>Elisha, I.L., F.S. Botha, L.J. McGaw and J.N. Eloff,2017Escherichia coli against five other bacteria and cytotoxicity of extracts.]]>2017Tchinda, C.F., I.K. Voukeng, V.P. Beng and V. Kuete,2017Albizia adianthifolia, Alchornea laxiflora, Laportea ovalifolia and three other cameroonian plants against multi-drug resistant gram-negative bacteria. ]]>24950955Moubayed, N.M.S., H.J. Al Houri, M.M. Al Khulaifi and D.A. Al Farraj,201724162169Amber, R., M. Adnan, A. Tariq, S.N. Khan and S. Mussarat et al.,201825154161Dzotam, J.K., F.K. Touani and V. Kuete,2016Canarium schweinfurthii and four other cameroonian dietary plants against multi-drug resistant gram-negative bacteria.]]>23565570Amaral, G.P., C.R. Mizdal, S.T. Stefanello, A.S.L. Mendez and R.L. Puntel et al.,2019Rosmarinus officinalis L. extract and its fractions.]]>9383392Arulkumar, A., K. Sampath Kumar and S. Paramasivam,2020in vitro antioxidant potential of Indian mangroves.]]>2020Wang, N., X. Liu, J. Li, Q. Zhang and X. Li et al.,2020Chimonanthus salicifolius S. Y. Hu. leaves.]]>2020Maheshwari, M., A.S. Althubiani, H.H. Abulreesh, F.A. Qais, M.S. Khan and I. Ahmad,2019Carum copticum L. enhances efficacy of ciprofloxacin against MDR enteric bacteria.]]>2618481855Goudjil, M.B., S. Zighmi, D. Hamada, Z. Mahcene, S.E. Bencheikh and S. Ladjel,2020Thymus capitatus (Lamiaceae).]]>128274282Achika, J.I., R.G. Ayo, A.O. Oyewale and J.D. Habila,2020Uapaca heudelotti.]]>2020Abuga, I., S.F. Sulaiman, R.A. Wahab, K.L. Ooi and M.S.B.A. Rasad,2020In vitro antibacterial effect of the leaf extract of Murraya koenigii on cell membrane destruction against pathogenic bacteria and phenolic compounds identification.]]>2020El-Atki, Y., I. Aouam, F. El-Kamari, A. Taroq, B. Lyoussi, B. Oumokhtar and A. Abdellaoui,2020Teucrium polium L. subspecies: preventive approach against nosocomial infections.]]>1338663874Xia, Y.T., G.K.L. Chan, H.Y. Wang, T.T.X. Dong and R. Duan et al.,2020Scutellaria baicalensis: Potential application as an additive in aquaculture feedings.]]>2020Rattanasuk, S. and T. Phiwthong,2020Spathiphyllum wallisii extracts against human pathogenic bacteria.]]>2314361441Le Moullec, A., O.J. Juvik and T. Fossen,2015Zamioculcas zamiifolia-A drought resistant survivor through millions of years.]]>106280285Seneviratne, K.A.C.N., W.A.M. Daundasekera, S.A. Kulasooriya and D.S.A. Wijesundara,2013Zamioculcas zamiifolia.]]>425562Sriprapat, W. and P. Thiravetyan,2013Zamioculcas zamiifolia.]]>2013Hettiarachchi, S.A., S.J. Lee, Y. Lee, Y.K. Kwon and M. De Zoysa et al.,20172714411448Ratananikom, K. and N. Srikacha,2020in vitro experiment.]]>9223226Trinh, P.C., L.T.T. Thao, H.T.V. Ha and T. Nguyen,20202020Diarra, M.S., Y.I. Hassan, G.S. Block, J.C.G. Drover, P. Delaquis and B.D. Oomah2020Vaccinium macrocarpon) fruit pomace against Listeria spp.]]>2020Ceruso, M., J.A. Clement, M.J. Todd, F. Zhang and Z. Huang et al.,2020Listeria monocytogenes.]]>2020