O. T. Foye
Department of Poultry Science, North Carolina State University, Raleigh, NC 27695-7608, USA
C. Ashwell
Department of Poultry Science, North Carolina State University, Raleigh, NC 27695-7608, USA
Z. Uni
Department of Animal Sciences, Agriculture Faculty, Hebrew University of Jerusalem, Israel
P. R. Ferket
Department of Poultry Science, North Carolina State University, Raleigh, NC 27695-7608, USA
ABSTRACT
In-ovo Feeding (IOF), injecting nutrients into the amnion of the developing embryo may enhance post-hatch growth by enhancing intestinal expression and function prior to hatch. This hypothesis was evaluated with IOF solutions of Arginine (ARG), HMB and Egg White Protein (EW) in turkeys. Four treatments were arranged as a factorial of 2 levels of ARG (0 and 0.7%) and HMB (0 and 0.1%). An IOF solution of EW (18%) was evaluated for contrast. At 23 d of incubation (23E) each IOF solution was injected into the amnion. Upon hatch all poults were fed ad libitum. Intestinal mRNA of the digestion/absorption related genes Sodium Glucose Transporter (SGLT), Peptide transporter (Pept), Sucrase-isomaltase (SI) and Aminopepdiase (AP) were determined at 25E, hatch, 3 and 7 d by real-time PCR analysis. The data was analyzed as a 2X2 factorial and 1-way ANOVA for contrast. There were significant ARG X HMB effects on Pept, SGLT, SI and AP mRNA levels at hatch. IOF HMB alone enhanced Pept, SGLT, SI and AP intestinal mRNA expression at hatch, whereas inclusion of ARG depressed expression. There were main and independent effects of HMB or ARG on mRNA expression of SI and AP at 25E, in which ARG alone depressed expression, while IOF HMB alone had no effect on SI or AP expression. These results suggest that IOF may enhance early growth by improving intestinal capacity to digest and absorb nutrients at hatch which may fuel more rapid post-hatch growth.
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How to cite this article
O. T. Foye, C. Ashwell, Z. Uni and P. R. Ferket, 2009. The Effects of Intra-Amnionic Feeding of Arginine And/or ß-Hyroxy-ß-Methylbutyrate on Jejunal Gene Expression in the Turkey Embryo and Hatchling. International Journal of Poultry Science, 8: 437-445.
DOI: 10.3923/ijps.2009.437.445
URL: https://scialert.net/abstract/?doi=ijps.2009.437.445
DOI: 10.3923/ijps.2009.437.445
URL: https://scialert.net/abstract/?doi=ijps.2009.437.445
REFERENCES
- Buddington, R.K., J.W. Chen and J.M. Diamond, 1991. Dietary regulation of intestinal brush-border sugar and amino acid transport in carnivores. Am. J. Physiol. Soc., 261: 793-801.
Direct Link - Butzner, J.D. and D.G. Gall, 1990. Impact of refeeding on intestinal development and function in infant rabbits subjected to protein-energy malnutrition. Pediatr. Res., 27: 245-251.
PubMedDirect Link - Caviedes-Vidal, E., D. Afik, C.M. Del Rio and W.H. Karasov, 2000. Dietary modulation of intestinal enzymes of the house sparrow (Passer domesticus): Testing an adaptive hypothesis. Comp. Biochem. Physiol. A, 125: 11-24.
CrossRef - Diamond, J.M. and W.H. Karasov, 1987. Adaptive regulation of intestinal nutrient transporters. Proc. Natl. Acad. Sci., 84: 2242-2245.
PubMedDirect Link - Diamond, J.M., W.H. Karasov, C. Cary, D. Enders and R. Yung, 1984. Effect of dietary carbohydrate on monosaccharide uptake by mouse small intestine in vitro. J. Physiol., 349: 419-440.
PubMedDirect Link - Erickson, R.H., J.R.G. Gum, M.M. Lindstrom, D. McKean and Y.S. Kim, 1995. Regional expression and dietary regulation of rat small intestinal peptide and amino acid transporter mRNAs. Biochem. Biophys. Res. Commun., 216: 249-257.
Direct Link - Ferraris, R.P., 2001. Dietary and developmental regulation of intestinal sugar transport. Biochem. J., 360: 265-276.
PubMedDirect Link - Ferraris, R.P. and J.M. Diamond, 1989. Specific regulation of intestinal nutrient transporters by their dietary substrates. Annu. Rev. Physiol., 51: 125-141.
CrossRefDirect Link - Ferraris, R.P. and J.M. Diamond, 1992. Crypt-villus site of glucose transporter induction by dietary carbohydrate in mouse intestine. Am. J. Physiol., 262: 1069-1073.
Direct Link - Ferraris, R.P. and J.M. Diamond, 1993. Crypt-villus site of substrate-dependent regulation of mouse intestinal glucose transporters. Proc. Natl. Acad. Sci. USA., 90: 5868-5872.
PubMedDirect Link - Ferraris, R.P. and J.M. Diamond, 1997. Regulation of intestinal sugar transport. Physiol. Rev., 77: 257-302.
Direct Link - Ferraris, R.P., W.W. Kwan and J.M. Diamond, 1988. Regulatory signals for intestinal amino acid transporters and peptidases. Am. J. Physiol., 255: 151-157.
Direct Link - Foye, O.T., Z. Uni and P.R. Ferket, 2006. Effect of in ovo feeding egg white protein, β-hydroxy-β-methylbutyrate and carbohydrates on glycogen status and neonatal growth of turkeys. Poult. Sci., 85: 1185-1192.
CrossRefPubMedDirect Link - Foye, O.T., P.R. Ferket and Z. Uni, 2007. The effects of in ovo feeding arginine, β-hydroxy-β-methyl-butyrate and protein on jejunal digestive and absorptive activity in embryonic and neonatal Turkey poults. Poult. Sci., 86: 2343-2349.
CrossRefDirect Link - Geyra, A., Z. Uni, O. Gal-Garber, D. Guy and D. Sklan, 2002. Starving affects cdx gene expression during small intestinal development in the chick. J. Nutr., 132: 911-917.
Direct Link - Geyra, A., Z. Uni and D. Sklan, 2001. The effect of fasting at different ages on growth and tissue dynamics in the small intestine of the young chick. Br. J. Nutr., 86: 53-61.
CrossRefPubMedDirect Link - Jiang, L. and R.P. Ferraris, 2001. Developmental reprogramming of rat GLUT-5 requires de novo mRNA and protein synthesis. Am. J. Physiol., 280: 113-120.
Direct Link - Karasov, W.H., D.H. Solberg and J.M. Diamond, 1987. Dependence of intestinal amino acid uptake on dietary protein or amino acid levels. Am. J. Physiol., 252: 614-625.
Direct Link - Karasov, W.H. and E.S. Debnam, 1987. Rapid adaptation of intestinal glucose transport: A brush-border or basolateral phenomenon? Am. J. Physiol., 253: 54-61.
Direct Link - Kishi, K., T. Tanaka, M. Igawa, S. Takase and T. Goda, 1999. Sucrase-isomaltase and hexose transporter gene expressions are coordinately enhanced by dietary fructose in rat jejunum. J. Nutr., 129: 953-956.
Direct Link - Matsushita, S., 1985. Development of sucrase in the chick small intestine. J. Exp. Biol. Zool., 233: 377-383.
CrossRefDirect Link - Miyamoto, K., K. Hase, T. Takagi, T. Fujii and Y. Taketani et al., 1993. Differential responses of intestinal glucose transporter mRNA transcripts to levels of dietary sugars. Biochem. J., 295: 211-215.
PubMedDirect Link - Moran, Jr. E.T. and B.S. Reinhart, 1980. Poult yolk sac amount and composition upon placement: Effect of breeder age, egg weight, sex and subsequent change with feeding or fasting. Poult. Sci., 59: 1521-1528.
CrossRefPubMedDirect Link - Noble, R.C. and D. Ogunyemi, 1989. Lipid changes in the residual yolk and liver of the chick immediately after hatching. Biol. Neonate, 56: 228-236.
CrossRefPubMedDirect Link - Noy, Y., A. Geyra and D. Sklan, 2001. The effect of early feeding on growth and small intestine development in the posthatch poult. Poult. Sci., 80: 912-919.
Direct Link - Sell, J.L., 1989. Intestinal disaccharidases of young turkeys: Temporal development and influence of diet composition. Poult. Sci., 68: 265-277.
PubMedDirect Link - Sharp, P.A., E.S. Debnam and S.K. Srai, 1996. Rapid enhancement of brush border glucose uptake after exposure of rat jejunal mucosa to glucose. Gut, 39: 545-550.
PubMedDirect Link - Siddons, R.C., 1969. Intestinal disaccharidase activities in the chick. Biochem. J., 112: 51-59.
CrossRefPubMedDirect Link - Sklan, D., 2001. Development of the digestive tract of poultry. World's Poult. Sci. J., 57: 415-428.
CrossRefDirect Link - Sklan, D., A. Geyra, E. Tako, O. Gal-Gerber and Z. Uni, 2003. Ontogeny of brush border carbohydrate digestion and uptake in the chick. Br. J. Nutr., 89: 747-753.
Direct Link - Smith, M.W., M.A. Mitchell and M.A. Peacock, 1990. Effects of genetic selection on growth rate and intestinal structure in the domestic fowl (Gallus domesticus). Comp. Biochem. Physiol. A: Comp. Physiol. 97: 57-63.
PubMedDirect Link - Tako, E., P.R. Ferket and Z. Uni, 2004. Effects of in ovo feeding of carbohydrates and β-hydroxy-β-methylbutyrate on the development of chicken intestine. Poult. Sci., 83: 2023-2028.
Direct Link - Traber, P.G., 1997. Epithelial cell growth and differentiation V. transcriptional regulation, development and neoplasia of the intestinal epithelium. Am. J. Physiol., 273: 979-981.
Direct Link - Uni, Z., A. Geyra, H. Ben-Hur and D. Sklan, 2000. Small intestinal development in the young chick: Crypt formation and enterocyte proliferation and migration. Br. Poult. Sci., 41: 544-551.
CrossRefPubMedDirect Link - Uni, Z., E. Tako, O. Gal-Garber and D. Sklan, 2003. Morphological, molecular and functional changes in the chicken small intestine of the late-term embryo. Poult. Sci., 82: 1747-1754.
Direct Link - Uni, Z. and P. Ferket, 2004. Methods for early nutrition and their potential. World Poult. Sci. J., 60: 101-111.
CrossRefDirect Link - Uni, Z., P.R. Ferket, E. Tako and O. Kedar, 2005. In ovo feeding improves energy status of late-term chicken embryos. Poult. Sci., 84: 764-770.
PubMedDirect Link - Uni, Z., S. Ganot and D. Sklan, 1998. Posthatch development of mucosal function in the broiler small intestine. Poult. Sci., 77: 75-82.
CrossRefDirect Link - Uni, Z., Y. Noy and D. Sklan, 1999. Posthatch development of small intestinal function in the poult. Poult. Sci., 78: 215-222.
CrossRefPubMedDirect Link - Yasutake, H., T. Goda and S. Takase, 1995. Dietary regulation of sucrase-isomaltase gene expression in rat jejunum. Biochim. Biophys. Acta, 243: 270-276.
PubMedDirect Link