Hesham Sultan
Department of Poultry and Rabbit Diseases, Faculty of Veterinary Medicine, Minoufiya University, Minoufiya , Egypt
Hussein A. Hussein
Department of Virology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt
Alaa G. Abd El-Razik
Department of Poultry and Rabbit Diseases, Faculty of Veterinary Medicine, Minoufiya University, Minoufiya , Egypt
Sallah El-Balall
Department of Pathology, Faculty of Veterinary Medicine, Minoufiya University, Minoufiya, Egypt
Shaima M. Talaat
Department of Poultry and Rabbit Diseases, Faculty of Veterinary Medicine, Minoufiya University, Minoufiya , Egypt
Awad A. Shehata
Institute of Microbiology, Faculty of Veterinary Medicine, Leipzig University, Leipzig, Germany
ABSTRACT
The efficacy of a turkey herpesvirus (HVT-IBD) vector vaccine encoding the VP2 gene of Infectious Bursal Disease (IBD) was evaluated in comparison with classic vaccines on two commercial broiler chicken farms (A and B), with high levels of Maternal Derived Antibodies (MDA). The HVT-IBD vaccine was administrated into chickens of farm A at 1-day-old while intermediate and intermediate-plus vaccines were given at 1-and 14-day-old into chickens of farm B, respectively. An early significant seroconversion was detected at 21-day-old in chickens of farm A, while no significant serological response was detected in farm B at this time. The antibody level was significantly higher in chickens in farm A at 28-and 35-day-old. Moreover, HVT-IBD vaccine provided complete protection against recent Egyptian vvIBDV isolate. In conclusion, HVT-IBD vaccine has the ability to induce an immune response in birds with high levels of MDA and could protect against recent Egyptian vvIBDV isolates.
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How to cite this article
Hesham Sultan, Hussein A. Hussein, Alaa G. Abd El-Razik, Sallah El-Balall, Shaima M. Talaat and Awad A. Shehata, 2012. Efficacy of HVT-IBDV Vector Vaccine Against Recent Egyptian vvIBDV in Commercial
Broiler Chickens. International Journal of Poultry Science, 11: 710-717.
DOI: 10.3923/ijps.2012.710.717
URL: https://scialert.net/abstract/?doi=ijps.2012.710.717
DOI: 10.3923/ijps.2012.710.717
URL: https://scialert.net/abstract/?doi=ijps.2012.710.717
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