S.J. Sherajee
Department of Pharmacology,
Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
K. Rafiq
Department of Pharmacology,
Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
N.S. Juyena
Department of Pharmacology,
Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
S. Ahmed
Department of Pharmacology,
Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
M.A. Hashim
Department of Pharmacology,
Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
ABSTRACT
To find out the effect of diazepam and promethazine hydrochloride on respiratory rate, pulse rate, temperature and production of clinical signs in goats and also to compare the effect of 2% lignocaine hydrochloride and 0.5% bupivacaine hydrochloride during paravertebral and epidural analgesia were investigated. A total of 16 apparently healthy Black Bengal goats with body weight of 8-12 (median 9.5 kg) kg were used and allocated in 8 groups. Both diazepam and promethazine, were used as sedatives. Diazepam and promethazine produced significant reduction (P<0.01) of respiratory rate and significantly (P<0.01) increase of the pulse rate, respectively. But both drugs produced reduction of temperature insignificantly. The important clinical signs recorded using diazepam was movement of legs, neck, salivation and sleepiness whereas with promethazine only a tranquilizing effect was recorded. With 2% lignocaine hydrochloride the onset of analgesia was rapid compared to 0.5 bupivacaine hydrochloride. But the duration was significantly longer in 0.5% bupivacaine than that of 2% lignocaine hydrochloride. Muscle relaxation was better with 2% lignocaine hydrochloride compared to 0.5% bupivacaine hydrochloride. This experiment suggested that both diazepam and promethazine are suitable as pre-medicants in goats and bupivacaine seemed to be better for longer duration of analgesia compared to lignocaine which may be used for shorter and minor surgery in goats.
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How to cite this article
S.J. Sherajee, K. Rafiq, N.S. Juyena, S. Ahmed and M.A. Hashim, 2003. Combined Sedation and Regional Analgesia in Black Bengal Goats of Bangladesh. Journal of Biological Sciences, 3: 1140-1147.
DOI: 10.3923/jbs.2003.1140.1147
URL: https://scialert.net/abstract/?doi=jbs.2003.1140.1147
DOI: 10.3923/jbs.2003.1140.1147
URL: https://scialert.net/abstract/?doi=jbs.2003.1140.1147
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