Uzma Malik
Department of Biological Sciences, University of Arid Agriculture, Rawalpindi, Pakistan
Noor-us-Saba
Bacteriology Laboratory, Public Health Division, National Institute of Health, Islamabad, Pakistan
Ali Abbas Qazilbash
United Nations Industrial Development Organization, Islamabad, Pakistan
ABSTRACT
Strains of Streptococcus pyogenes and Streptococcus pneumoniae, isolated from clinical samples (125 throat swabs and 100 sputum) from patients suffering from sore throat and pneumonia infections, were subjected to a series of culture sensitivity tests against known antibiotics to determine their antibiogram patterns. Of the S. pyogenes isolates, all were found to be sensitive to penicillin and cefrioxone, whereas some of the strains showed complete resistance against cotrimoxazole (88.9%), oxacillin (22.2%), cephradine (22.2%) and erythromycin (11.1%). As for the S. pneumoniae strains, all the isolates in this study were sensitive to vancomycin and cephradine, whereas 80% showed complete resistance to kanamycin, 60% to gentamycin, 20% to cotrimoxazole, 20% to tetracycline and 10% to penicillin. Strains of S. pneumoniae (20%) displayed intermediate resistance to erythromycin. Inadequate diagnostic procedures, un-supervised, improper use of antibiotics and easy access to prescription drugs may contribute to the rise of resistant strains. To combat such trends approved strategies must encompass legislative enforcement through strict enforcement of the laws related to sales of prescription drugs, involvement of clinicians, pharmacies and civil society pressure groups to ensure the rational and correct use of prescription drugs.
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How to cite this article
Uzma Malik, Noor-us-Saba and Ali Abbas Qazilbash, 2005. Antibiogram Sensitivity Pattern of Streptococcus pyogenes and Streptococcus
pneumoniae Isolated from Patients with Sore Throat and Pneumonia
Infections. Pakistan Journal of Biological Sciences, 8: 1146-1151.
DOI: 10.3923/pjbs.2005.1146.1151
URL: https://scialert.net/abstract/?doi=pjbs.2005.1146.1151
DOI: 10.3923/pjbs.2005.1146.1151
URL: https://scialert.net/abstract/?doi=pjbs.2005.1146.1151
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