Hamid Nasri
Department of Internal Medicine, Shahrekord University of Medical Sciences,
Hajar Medical, Educational and Therapeutic Center, Shahrekord, Iran
Azar Baradaran
Department of Biochemistry, Center of Research and Reference Laboratory oflran,
Hospital Bu Ali, Damavand st., P.O. Box: 17115-365, Tehran, Iran 17117
ABSTRACT
The aim of present study was the assessment of relationships between PTH abnormalities and the parameter of Helicobacter pylori (H. pylori) infection as expressed by concentration of IgG antibodies against H. pylori. The study was carried out on 44 (F = 17, M = 27) stable hemodialysis (HD) patients with upper gastrointestinal symptoms. A significant positive correlations of H. pylori IgG antibody titers with serum iPTH and phosphorus also a significant inverse correlation of H. pylori IgG antibody titers with serum alkalin phosphatase was found. It is known that hyperparathyroidism is connected with stimulation of gastrin synthesis as well with increased acidity of gastric juice. Hypergastrinaemia induced stimulation of gastrin synthesis and resultant increased acidity of gastric juice could intensify the H. pylori infection in hemodialysis patients. We strongly propose to more study on the association of secondary hyperparathyroidism with H. pylori infection, because both dyspeptic symptoms and secondary hyperparathyroidism are quite common in chronic hemodialysis patients and in the meantime needs more attention toward control of high levels of parathormone in HD patients.
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How to cite this article
Hamid Nasri and Azar Baradaran, 2006. Helicobacter Pylori IgG Antibodies in Association with Secondary Hyperparathyroidism in End-stage Renal Failure Patients Undergoing Regular Hemodialysis. Pakistan Journal of Biological Sciences, 9: 133-136.
DOI: 10.3923/pjbs.2006.133.136
URL: https://scialert.net/abstract/?doi=pjbs.2006.133.136
DOI: 10.3923/pjbs.2006.133.136
URL: https://scialert.net/abstract/?doi=pjbs.2006.133.136
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